(S)-3-Hydroxypiperidine

(S)-3-Hydroxypiperidine Basic information
Product Name:(S)-3-Hydroxypiperidine
Synonyms:(S)-3-Hydroxypiperidine;(3S)-piperidin-3-ol;(S)-Piperidin-3-ol;(3S)-3-Piperidinol;3-Piperidinol, (3S)-
CAS:24211-55-0
MF:C5H11NO
MW:101.15
EINECS:
Product Categories:
Mol File:24211-55-0.mol
(S)-3-Hydroxypiperidine Structure
(S)-3-Hydroxypiperidine Chemical Properties
Boiling point 191.9±23.0 °C(Predicted)
density 1.016±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka14.91±0.20(Predicted)
Safety Information
HS Code 2933399990
MSDS Information
(S)-3-Hydroxypiperidine Usage And Synthesis
Uses(3S)-3-Piperidinol-D4 is an intermediate used in the synthesis of Ibrutinib-d4 (I124971), which is the labeled analogue of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
(S)-3-Hydroxypiperidine Preparation Products And Raw materials
(R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one Ibrutinib Impurity 24 Ibrutinib (S)-Ibrutinib Ibrutinib Dimer Impurity Ibrutinib Impurity 28 Ibrutinib Impurity 25 Acrylic anhydride 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Ibrutinib Impurity 30 (S)-1-Boc-3-hydroxypiperidine Ibrutinib Impurity 3 Ibrutinib Impurity 6 Ibrutinib Impurity 18 Ibrutinib Impurity 37 5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine 2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]- N-BOC-2-HYDROXYPIPERIDINE

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