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Clozapine EP IMpurity D

Clozapine EP IMpurity D Basic information
Product Name:Clozapine EP IMpurity D
Synonyms:Clozapine EP IMpurity D;[2-[(2-AMino-4-chlorophenyl)aMino]phenyl](4-Methyl-1-piperazinyl)Methanone;1-[2-[(2-Amino-4-chlorophenyl)amino]benzoyl]-4-methylpiperazine;Clozapine Impurity 4(Clozapine EP Impurity D);[2-(2-amino-4-chloroanilino)phenyl]-(4-methylpiperazin-1-yl)methanone;2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide;Clozapine impurity 4/Clozapine EP Impurity D/Clozapine impurity B (USP)/(2-((2-amino-4-chlorophenyl)amino)phenyl)(4-methylpiperazin-1-yl)methanone;1-[2-[(2-Amino-4-chlorophenyl)amino
CAS:65514-71-8
MF:C18H21ClN4O
MW:344.84
EINECS:
Product Categories:Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:65514-71-8.mol
Clozapine EP IMpurity D Structure
Clozapine EP IMpurity D Chemical Properties
Melting point >103°C (dec.)
Boiling point 513.2±50.0 °C(Predicted)
density 1.297±0.06 g/cm3(Predicted)
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
pka6.68±0.10(Predicted)
form Solid
color Pale Red to Red
Safety Information
MSDS Information
Clozapine EP IMpurity D Usage And Synthesis
UsesClozapine EP IMpurity D is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.
Clozapine EP IMpurity D Preparation Products And Raw materials
Preparation ProductsClozapine
2-[(4-CHLORO-2-NITROPHENYL)AMINO]-BENZOIC ACID CLOZAPINE N-OXIDE 8-Chloro-5,10-dihydrodibenzo[b,e][1,4]diazepin-11-one Clozapine N-DESMETHYLCLOZAPINE 11,11'-(PIPERAZINE-1,4-DIYL)-BIS-8-CHLORO-5H-DIBENZE[B,E][1,4]-DIAZEPINE
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