Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid)

Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) Basic information
Product Name:Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid)
Synonyms:Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid);Anastrozole Mono Acid;Anastrozole Impurity 4;2-(3-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2-cyanopropan-2-yl)phenyl)-2-methylpropanoic acid;Benzeneacetic acid, 3-(1-cyano-1-methylethyl)-α,α-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-;3-(1-Cyano-1-methylethyl)-alfa,alfa-dimethyl-5-(1H-,1,2,4-triazole-1-ylmethyl)-benzeneacetic acid;Anastrazole imp (Mono acid and mono CN);Anastrozole Monoacid Impurity
CAS:1338800-82-0
MF:C17H20N4O2
MW:312.37
EINECS:
Product Categories:Aromatics, Inhibitors, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1338800-82-0.mol
Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) Structure
Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) Chemical Properties
Melting point 163-165°C
storage temp. Refrigerator
solubility Chloroform (Slightly, Heated), DMSO (Sparingly), Methanol (Slightly, Heated)
form Solid
color White to Off-White
Safety Information
MSDS Information
Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) Usage And Synthesis
UsesAnastrozole Mono Acid is an impurity of Anastrozole (A637435), an aromatase enzyme inhibitor and antineoplastic agent.
Anastrozole IMpurity (3-(1-Cyano-1-Methylethyl)-alfa,alfa-diMethyl-5-(1H-,1,2,4-triazole-1-ylMethyl)-benzeneacetic acid) Preparation Products And Raw materials
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-4-ylmethyl)phenyl]-2-methyl-propaneni 2-[3-CHLOROMETHYL-5-(CYANO-DIMETHYL-METHYL)-PHENYL]-2-METHYL-PROPIONITRILE Anastrozole iMpurity A Anastrozole p-Toluenesulfonic acid monohydrate 3,5-Bis(bromomethyl)toluene Anastrozole iMpurity E Anastrozole iMpurity D Anastrozole IMpurity (2-(3-((1H-1,2,4-triazol-1-yl)Methyl)-5-(1-aMino-2-Methyl-1-oxopropan-2-yl)phenyl)-2-Methylpropanoi Anastrozole iMpurityC Anastrozole IMpurity (alfa1 , alfa1, alfa3, alfa3-TetraMethyl-5-(1H-1,2,4-triazol-1-ylMethyl)-1,3-Benzenediacetic acid) α,α,α’,α’-Tetramethyl-5-(dibromomethyl)-1,3-benzenediacetonitrile Anastrozole Dimer Impurity Anastrozole iMpurity Anastrozole N-glucuronide 5-Methyl-1,3-benzenediacetonitrile Anastrozole Impurity 11 Di-Destriazole Anastrozole DiMer IMpurity

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