[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl]

[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Basic information
Product Name:[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl]
Synonyms:[6-Hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-7-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]Methanone;[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl];3-Des[4-(2-Piperidinyl)ethoxy]benzoyl-7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene;Raloxifene IMpurity C;(6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone;Raloxifene Impurity 2(Raloxifene EP Impurity B);[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-7-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone;(6-hydroxy-2-(4-methoxyphenyl)benzo[b]thiophen-3-yl)(4-(2-(piperidin-1-yl)ethoxy)phenyl)methanone hydrochloride
CAS:1391054-73-1
MF:C28H27NO4S
MW:473.58
EINECS:
Product Categories:Aromatics;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Mol File:1391054-73-1.mol
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Structure
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Chemical Properties
Melting point >109°C (dec.)
Boiling point 681.3±55.0 °C(Predicted)
density 1.289±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka7.74±0.50(Predicted)
color Dark Yellow to Orange
Safety Information
MSDS Information
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Usage And Synthesis
UsesAm impurity of the nonsteroidal, selective estrogen receptor modulator (SERM), Raloxifene (R100000).
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-7-yl] Preparation Products And Raw materials
Raloxifene Impurity 19 Raloxifene N-Oxide 1-(2-Chloroethyl)piperidine hydrochloride [6-hydroxy-7-[6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-piperidin-1-ylethoxy)benzoyl]-1-benzothiophen-7-yl]-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone 2-(4-METHOXY PHENYL)BENZOTHIOPHENE-6-OL LY 88074 Raloxifene Impurity 21 2-[4-[(Methylsulfonyl)oxy]phenyl]-Benzo[b]thiophene-6-ol 6-Methanesulfonate Raloxifene Impurity Raloxifene 6'-glucuronide Raloxifene hydrochloride Raloxifene Impurity 1 2-(4-Hydroxyphenyl)benzo[b]thiophene-6-ol 7-[4-(2-Piperidinyl)ethoxy]benzoyl Raloxifene (Raloxifene Impurity) RALOXIFENE-D4, HYDROCHLORIDE Raloxifene EP IMpurity A Raloxifene Impurity 18 4-(3-(Piperidin-1-yl)propoxy)benzoic acid

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