Desloratadine Epoxide

Desloratadine Epoxide Basic information
Product Name:Desloratadine Epoxide
Synonyms:Desloratadine Epoxide;Epoxy Desloratadine;8-Chloro-5,6-dihydrodispiro[benzo[5,6]cyclohepta[1,2-b]pyridine-11,2'-oxirane-3',4''-piperidine
CAS:1346604-23-6
MF:C19H19ClN2O
MW:326.82
EINECS:
Product Categories:Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Aromatics;Heterocycles
Mol File:1346604-23-6.mol
Desloratadine Epoxide Structure
Desloratadine Epoxide Chemical Properties
Melting point >145°C (dec.)
storage temp. -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Safety Information
MSDS Information
Desloratadine Epoxide Usage And Synthesis
UsesAn impurity of the histamine H1-receptor antagonist Desloratadine (D290250).
Desloratadine Epoxide Preparation Products And Raw materials
Desloratadine IMpurity B Desloratadine D5 DESLORATADINE-D4 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d 1-Oxide Desloratadine IMpurity 3 Iso Desloratadine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine 8-Dechloro-9-chloro Desloratadine Desloratadine Citric Amide Desloratadine Pyridine N-oxide Desloratadine-d7 (Major) 8-Deschloro-8-bromo-N-methyl Desloratadine IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate 5,6-Dehydro-N-methyl Desloratadine Desloratadine N-Carboxylic Acid Methyl Ester Desloratadine IMpurity 6 Desloratadine N-Hydroxypiperidine Desloratadine IMpurity 1

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