ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards O-De(3-fluorobenzyl) Lapatinib

O-De(3-fluorobenzyl) Lapatinib

O-De(3-fluorobenzyl) Lapatinib Basic information
Product Name:O-De(3-fluorobenzyl) Lapatinib
Synonyms:O-De(3-fluorobenzyl) Lapatinib;Lapatinib IMpurity 1;2-chloro-4-((6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-yl)amino)phenol;Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib);Lapatinib Impurity 20;Lapatinib Impurity 1 (O-De(3-fluorobenzyl) Lapatinib) Ditosylate Salt;Lapatinib Impurity 35;Lapatinib O-Desfluorobenzyl Imp
CAS:1268997-70-1
MF:C22H21ClN4O4S
MW:472.94
EINECS:
Product Categories:Heterocycles;Intermediates & Fine Chemicals;Aromatics;Metabolites & Impurities;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:1268997-70-1.mol
O-De(3-fluorobenzyl) Lapatinib Structure
O-De(3-fluorobenzyl) Lapatinib Chemical Properties
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Pale Yellow to Yellow
Safety Information
MSDS Information
O-De(3-fluorobenzyl) Lapatinib Usage And Synthesis
UsesA reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.
O-De(3-fluorobenzyl) Lapatinib Preparation Products And Raw materials
Lapatinib iMpurity Lapatinib Impurity 16 Lapatinib impurity L Lapatinib 4-Fluoro Impurity N-De[2-(Methylsulfonyl)ethyl] Lapatinib Lapatinib IMpurity 8 Lapatinib IMpurity 10 LOXO-101 3-Chloro-4-(3-fluorobenzyloxy)aniline Lapatinib 2-Fluoro Impurity 5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde Cabozantinib Lapatinib IMpurity 2 Lapatinib impurity K Lapatinib Lapatinib
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