ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 4-Defluoro-4-hydroxy Gefitinib

4-Defluoro-4-hydroxy Gefitinib

4-Defluoro-4-hydroxy Gefitinib Basic information
Product Name:4-Defluoro-4-hydroxy Gefitinib
Synonyms:4-Defluoro-4-hydroxy Gefitinib;Phenol, 2-chloro-4-[[7-Methoxy-6-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]-;2-Chloro-4-[[7-Methoxy-6-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]phenol;Gefitinib iMpurity B;2-chloro-4-[[7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenol;4-Desfluoro 4-Hydroxy Gefitinib metabolite;Gefitinib impurity 15/4-Defluoro-4-Hydroxy Gefitinib/2-chloro-4-((7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-yl)amino)phenol;Gefitinib 4-Desfluoro 4-Hydroxy
CAS:847949-50-2
MF:C22H25ClN4O4
MW:444.91
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
Mol File:847949-50-2.mol
4-Defluoro-4-hydroxy Gefitinib Structure
4-Defluoro-4-hydroxy Gefitinib Chemical Properties
Boiling point 596.9±50.0 °C(Predicted)
density 1.340±0.06 g/cm3(Predicted)
solubility DMSO (Slightly)
pka8.62±0.31(Predicted)
form Solid
color Brown to Dark Brown
Stability:Hygroscopic
Safety Information
MSDS Information
4-Defluoro-4-hydroxy Gefitinib Usage And Synthesis
UsesA metabolite of Gefitinib (G304000).
DefinitionChEBI: 4-defluoro-4-hydroxy Gefitinib is a member of quinazolines.
4-Defluoro-4-hydroxy Gefitinib Preparation Products And Raw materials
3-(3-morpholinylpropoxy)-4-methoxybenzonitrile Benzaldehyde, 2-amino-4-methoxy-5-[3-(4-morpholinyl)propoxy]- 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate Gefitinib-d6 Gefitinib Impurity 14 N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine N'-(4-Amino-2-cyanophenyl)-N,N-dimethylformamidine 3(2H)-Benzofuranone, 6-hydroxy-2-[(3-hydroxy-4-methoxyphenyl)methylene]-4-methoxy-5-methyl- 7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one 3-DesMorpholinyl-3-hydroxyethylaMino Gefitinib Gefitinib InterMediate B Gefitinib iMpurity 4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile 3,4-Dichloroaniline Gefitinib Impurity 35 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide Gefitinib N-Oxide 4,4'-(propane-1,3-diyl)bismorpholine
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