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Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate

Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Basic information
Product Name:Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
Synonyms:FLUORO-N,N,N',N'-TETRAMETHYLFORMAMIDINIUM HEXAFLUOROPHOSPHATE;FLUORO-N,N,N',N'-TETRAMETHYLFORMAMINDINIUM HEXAFLUOROPHOSPHATE;TETRAMETHYLFLUOROFORMAMIDIMIUM-HEXAFLUOROPHOSPHATE;TETRAMETHYLFLUOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE;TETRAMETHYL FLUOROFORMAMIDIUM HEXAFLUORO PHOSPHATE;TFFH;N,N,N',N'-TETRAMETHYLFLUOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE;N,N,N',N'-TETRAMETHYLFLUOROFORMAMIDINIUM HEXAFLUUOROPHOSPHATE
CAS:164298-23-1
MF:C5H12F7N2P
MW:264.12
EINECS:
Product Categories:pharmacetical
Mol File:164298-23-1.mol
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Structure
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Chemical Properties
Melting point 104-109 °C (lit.)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form Powder
color Yellow
Water Solubility Soluble in water.
CAS DataBase Reference164298-23-1(CAS DataBase Reference)
EPA Substance Registry SystemMethanaminium, N-[(dimethylamino)fluoromethylene]-N-methyl-, hexafluorophosphate(1-) (1:1) (164298-23-1)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
F 3-10-21
HS Code 29252900
MSDS Information
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Usage And Synthesis
Chemical PropertiesWhite to off-white powder or crystal
UsesN,N,N',N'-Tetramethylfluoroformamidinium hexafluorophosphate is a useful reagent for in situ conversion of carboxylic acids to acid fluorides. Particularly useful for the coupling of sterically hindered amino acids.
UsesFluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate is used as a reagent for synthesis of cationic antimicrobial β-2,2-amino acid derivatives, philanthotoxin analogues for inhibition of the ionotropic glutamate receptor, small β-peptidomimetics for antimicrobials and hydrazone ligation to assemble multifunctional viral nanoparticles.
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate Preparation Products And Raw materials
Raw materialsTriphosgene-->Potassium fluoride-->Potassium hexafluorophosphate-->1,1,3,3-Tetramethylurea
HATU 1-(3-DIMETHYLAMINOPROPYL)-3-ETHYLCARBODIIMIDE METHIODIDE HBTU 1-Hydroxybenzotriazole N,N'-Diisopropylcarbodiimide Fluorine Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate 1,1,3,3-Tetramethylurea BIS(TETRAMETHYLENE)FLUOROFORMAMIDINIUM HEXAFLUOROPHOSPHATE FLUORO-N,N,N',N'-TETRAMETHYLFORMAMIDINIUM HEXAFLUOROPHOSPHATE (TFFH) 2-Fluoro-1,3-dimethylimidazolidinium hexafluorophosphate METHYL FLUORIDE 3-Dimethylaminopropylamine Hexaflumuron Hexafluorophosphoric acid Chlorfluazuron AMMONIUM HEXAFLUOROPHOSPHATE FLUORIDE Lithium hexafluorophosphate
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