| | SCHRADAN Basic information |
| Product Name: | SCHRADAN | | Synonyms: | schradan (bsi,iso,esa,jmaf);OMPA;OCTAMETHYLPYROPHOSPHORAMIDE;Octamethyl pyrophosphoramine;SCHRADAN;SCHADRAN;SCHRADEN;Recombinant Bacterial Outer Membrane Protein-A | | CAS: | 152-16-9 | | MF: | C8H24N4O3P2 | | MW: | 286.25 | | EINECS: | 205-801-0 | | Product Categories: | proteins | | Mol File: | 152-16-9.mol |  |
| | SCHRADAN Chemical Properties |
| Melting point | 17℃ | | Boiling point | bp0.5 120-125°; bp2.0 154° | | density | 1.24 g/cm3 (25 ºC) | | refractive index | 1.4698 (589.3 nm 20℃) | | pka | 0.85±0.70(Predicted) | | form | liquid | | color | Viscous liquid | | CAS DataBase Reference | 152-16-9 | | EPA Substance Registry System | Schradan (152-16-9) |
| Hazard Codes | T+ | | Risk Statements | 27/28 | | Safety Statements | 36/37-38-45 | | RIDADR | 3018 | | HazardClass | 6.1(a) | | PackingGroup | I | | HS Code | 29299090 | | Hazardous Substances Data | 152-16-9(Hazardous Substances Data) | | Toxicity | LD50 in male, female rats (mg/kg): 9.1, 42 orally; 15, 44 dermally (Gaines) |
| | SCHRADAN Usage And Synthesis |
| Chemical Properties | OMPA is a colorless liquid in crude form;
otherwise, it is a dark brown viscous liquid. | | Uses | Insecticide. | | Definition | ChEBI: Schradan is a phosphorodiamide. | | General Description | Schradan, octamethyl pyrophosphoramide(OMPA), bis[bisdimethylaminophosphonous] anhydride(Pestox III), is a viscous liquid that is miscible with waterand soluble in most organic solvents. It is not hydrolyzed byalkalies or water but is hydrolyzed by acids. Schradan isused as a systemic insecticide for plants, being absorbed bythe plants without appreciable injury. Insects feeding on theplant are incapacitated.
Schradan is a weak inhibitor of cholinesterases in vitro.In vivo, it is metabolized to the very strong inhibitor hydroxymethylOMPA. Hydroxymethyl OMPA is not stable andis metabolized further to the N-methoxide, which is a weakinhibitor of cholinesterase. | | General Description | Dark brown viscous liquid. Used as an insecticide and as an acaricide. Not registered as a pesticide in the U.S. | | Reactivity Profile | Organophosphates, such as SCHRADAN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides. | | Health Hazard | Extremely toxic; probable oral lethal dose in humans is 5-50 mg/kg, between 7 drops and 1 teaspoonful for a 150 lb. person. It is highly toxic when inhaled. Material is a cholinesterase inhibitor. It is similar in action to other organophosphorous pesticides in its toxicity. It is slightly less toxic than parathion. Gastrointestinal, neurologic and respiratory symptoms may accompany poisoning with SCHRADAN. High doses may cause a toxic psychosis similar to acute alcoholism. Persons taking phenobarbital and phenaglycodol together, glutethimide, chlorpromazine hydrochloride, or meprobamate may be at greater risk. These drugs appear to enhance the toxicity of the material markedly. | | Fire Hazard | When heated to decomposition, SCHRADAN can emit highly toxic fumes of oxides of phosphorus. Decomposes when mixed with acid. Hydrolyzed under acid conditions to dimethylamine and orthophosphoric acid. | | Safety Profile | Poison by ingestion, inhalation,skin contact, intraperitoneal, intravenous, subcutaneous,and ocular routes. Human systemic effects by ingestion: acholinesterase inhibitor. Has been found to inhibitperipheral cholinesterase without pronounced effects o | | Potential Exposure | Material is used as a systemic insecticide
for plants and as an acaricide. Not registered as a
pesticide in the United States. | | Shipping | UN3018 Organophosphorus pesticides, liquid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. | | Incompatibilities | Organophosphates are susceptible to formation
of highly toxic and flammable phosphine gas in the
presence of strong reducing agents such as hydrides and
active metals. Partial oxidation by oxidizing agents may
result in the release of toxic phosphorus oxides. Acids. | | Waste Disposal | In accordance with 40CFR165,
follow recommendations for the disposal of pesticides and
pesticide containers. Must be disposed properly by following
package label directions or by contacting your local or federal
environmental control agency, or by contacting your regional
EPA office. Consult with environmental regulatory agencies
for guidance on acceptable disposal practices. Generators of
waste containing this contaminant (≥100 kg/mo) must conform
with EPA regulations governing storage, transportation,
treatment, and waste disposal. |
| | SCHRADAN Preparation Products And Raw materials |
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