ChemicalBook Product Catalog API Antineoplastic agents Natural sources of antineoplastic 10-Hydroxycamptothecin

10-Hydroxycamptothecin

10-Hydroxycamptothecin Basic information
Product Name:10-Hydroxycamptothecin
Synonyms:10-HYDROXYCAMPTOTHECIN ACETATE;10-HYDROXYCAMPTOTHECIN ACETATE SALT;7-ETHYL-10-HYDROXY CAMPTHOTECIN;Hydroxy Camptothecine;77-Ethyl-10-hydroxy campthotecin;(20S)- 7-Ethyl-10-Hydroxycamptothecin;10-Hydroxycamp-totecin;7ETHYHYDROXYCAMPTOTHECIN
CAS:64439-81-2
MF:C20H16N2O5
MW:364.35
EINECS:613-598-9
Product Categories:Inhibitors;Antineoplastic;Camptothecin series
Mol File:64439-81-2.mol
10-Hydroxycamptothecin Structure
10-Hydroxycamptothecin Chemical Properties
Melting point 230-237°C
Boiling point 820.7±65.0 °C(Predicted)
density 1.60
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility DMSO: ≥ 37.5 mg/mL (102.92 mM)
pka8.93±0.40(Predicted)
form Pale yellow powder
color Yellow
InChIKeyLCZZWLIDINBPRC-FQEVSTJZSA-N
CAS DataBase Reference64439-81-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,T
Risk Statements 36/37/38-25
Safety Statements 26-36-45
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
RTECS UQ0491000
MSDS Information
ProviderLanguage
SigmaAldrich English
10-Hydroxycamptothecin Usage And Synthesis
Chemical Propertiesmp 268-270°C loss on drying <1%
Usestherapeutic effects for liver cancer, stomach, and neck cancer and leukemia.
UsesTopoisomerase inhibitor
10-Hydroxycamptothecin Preparation Products And Raw materials
10-Hydroxycamptothecin Topotecan RUBITECAN (+)-Camptothecin Hydroxyl camptothecine Lurtotecan Topotecan hydrochloride ACETIC ACID (S)-4-ETHYL-3,13-DIOXO-11-(2-TRIMETHYLSILANYL-ETHYL)-3,4,12,13-TETRAHYDRO-1H-2-OXA-6,12A-DIAZA-DIBENZO[B,H]FLUOREN-4-YL ESTER 10-METHOXYCAMPTOTHECIN 10-Hydroxycamptothecin IRINOTECAN-D10 HYDROCHLORIDE 7-Ethyl-10-hydroxycamptothecin 9-HYDROXYCAMPTOTHECIN, [12-3H(N)]- (S)-9-[(1,4'-BIPIPERIDIN)-1'-YL]METHYL-10-HYDROXYCAMPTOTHECIN 10-HYDROXYCAMPTOTHECIN Camtobell hydrochloride Irinotecan hydrochloride Exatecan
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