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| | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite Basic information |
| Product Name: | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite | | Synonyms: | P-REAGENT;2-Cyanoethoxybis(N,N-diisopropylaMino)phosphine;Bis(diisopropylaMino)(2-cyano;N,N,N',N'-Tetrakis(1-Methylethyl)phosphorodiaMidous Acid 2-Cyanoethyl Ester;THERAPEUTIC GRADE PHOS REAGENT;2-Cyanoethyl N,N,N',N'-tetra(prop-2-yl)phosphorodiamidoite;2-Cyanoethyl N,N,N',N'-tetrakis(isopropyl)phosphorodiamidite;β-Cyanoethyl-N,N,N`,N`-tertraisopropylphosphorodiaMidite | | CAS: | 102691-36-1 | | MF: | C15H32N3OP | | MW: | 301.41 | | EINECS: | 600-337-9 | | Product Categories: | OLED materials,pharm chemical,electronic;Building Blocks;Chemical Synthesis;Organic Building Blocks;Phosphoramidites;Phosphorus Compounds;Biochemistry;Nucleosides, Nucleotides & Related Reagents;Phosphorylating and Phosphorothioating Agents;Protecting Agents, Phosphorylating Agents & Condensing Agents;Regant series;Nucleic acids;Phosphorylating and Phosphitylating Agents | | Mol File: | 102691-36-1.mol |  |
| | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite Chemical Properties |
| | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite Usage And Synthesis |
| Chemical Properties | Clear to Cloudy Colourless Liquid | | Uses | Reagent for synthesizing phosphitylated nucleotides.1 | | Uses | 2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite was used:
- in preparation of prosphoramidite reagent, required for synthesis of 12-mer oligodeoxynucleotide
- as phosphorylating agent in synthesis of 1,2-diacyl-sn-glycerophosphatidylserine
- in situ preparation of deoxyribonucleoside phosphoramidites
- in preparation of 2′-deoxy-2′-fluoro-3′-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-5′-O-(4-methoxytrityl)-4′-thio-β-D-arabinouridine and 1-(3-O-(β-cyanoethyl-N,N-diisopropylphosphoramidic)-2-deoxy-2-fluoro-5-O-(4,4′-dimethoxytrityl)-4-thio-β-D-arabinofuranosyl)-thymine
- as reagent for synthesizing phosphitylated nucleotides
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| | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite Preparation Products And Raw materials |
| Raw materials | 5'-AMINO-5'-DEOXYTHYMIDINE-->BIS(DIISOPROPYLAMINO)CHLOROPHOSPHINE-->2-CYANOETHYL PHOSPHORODICHLORIDITE-->Diisopropylamine | | Preparation Products | Ceftibuten-->anionic starch-->DMT-DCYTIDINE (N6-BENZOYL) CYANOETHYL PHOSPHORAMIDITE)-->N4-(DIMETHYLAMINO)METHYLENE)-5'-O-(DIMETHOXYTRITYL)-2'-DEOXYGUANOSINE-3'-N,N-DIISOPROPYL (CYANOETHYL) PHOSPHORAMIDITE-->Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-(1,7-octadiyn-1-yl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]-->Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], (S)- (9CI)-->5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite-->3'-DA CEP-->5'-DMT-3'-O-TBDMS-N1-Me-Pseudouricdine-CE-Phosphoramidite-->4-THIO-DU CEP-->(2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-5-(3-(2,2,2-TRIFLUOROACETAMIDO)PROP-1-YNYL)-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE-->DMT-2'O-Methyl-rU Phosphoramidite |
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