3-(Hydroxymethyl)phenylboronic acid

3-(Hydroxymethyl)phenylboronic acid Basic information
Product Name:3-(Hydroxymethyl)phenylboronic acid
Synonyms:RARECHEM AH PB 0189;3-(HYDROXYMETHYL)PHENYLBORONIC ACID;3-(HYDROXYMETHYL)BENZENEBORONIC ACID;(3-Boronophenyl)methanol;3-Boronobenzyl alcohol;3-(Hydroxymethyl)phenylboronic Acid (contains varying amounts of Anhydride);3-(Hydroxymethyl)phenylboronic acid,97%;3-hydroxymethylboronic acid
CAS:87199-15-3
MF:C7H9BO3
MW:151.96
EINECS:
Product Categories:Boronic Acid;B (Classes of Boron Compounds);blocks;Aryl;Organoborons;Boronic Acids;BoronicAcids;Boric Acid;Boronic Acid series;Boronic Acids;Boronic Acids and Derivatives
Mol File:87199-15-3.mol
3-(Hydroxymethyl)phenylboronic acid Structure
3-(Hydroxymethyl)phenylboronic acid Chemical Properties
Melting point 95-99 °C (lit.)
Boiling point 380.5±44.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka8.31±0.10(Predicted)
form powder to crystal
color White to Almost white
Water Solubility Soluble in water.
BRN 8832019
CAS DataBase Reference87199-15-3(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-36-24/25
WGK Germany 3
HazardClass IRRITANT
HS Code 29319090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
3-(Hydroxymethyl)phenylboronic acid Usage And Synthesis
Chemical PropertiesOff-white Cryst
Usessuzuki reaction
UsesReactant used for copper-mediated trifluoromethylation, copper-catalyzed transformations from arylboronic acids in water, Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate. Reactant involved in the synthesis of biologically active molecules including Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions, HIV protease inhibitors with antiviral activity against drug-resistant viruses, Pyrrole derivatives for use as PDE4B inhibitors.
3-(Hydroxymethyl)phenylboronic acid Preparation Products And Raw materials
Preparation Products3-Aminobenzylalcohol-->(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol-->3-CYANOBENZYL ALCOHOL-->6-(3-(HYDROXYMETHYL)PHENYL)NAPHTHALEN-2-OL-->3-(4-Chlorophenyl)benzyl alcohol-->(4'-METHYLBIPHENYL-3-YL)-METHANOL
3-Carboxy-4-fluorophenylboronic acid 4-Tolylboronic acid 3-(Hydroxymethyl)phenylboronic acid 3-Carboxy-5-nitrophenylboronic acid 3-AMINO-5-METHOXYCARBONYLPHENYLBORONIC ACID, HCL 3-CARBOXY-2-FLUOROPHENYLBORONIC ACID (3-ACETOXYMETHYLPHENYL)BORONIC ACID PINACOL ESTER Ascoric Acid 3-METHOXYCARBONYL-5-NITROPHENYLBORONIC ACID 3-Carboxyphenylboronic acid Trimethylolpropane 3-Ethoxycarbonylphenylboronic acid 3,5-Dimethylphenylboronic acid 3-Amino-5-carboxylphenylboronic acid CARBOXYMETHYLCELLULOSE SODIUM SALT phosphoric acid 3-(ISOPROPOXYCARBONYL)PHENYLBORONIC ACID 3-BENZYLOXYCARBONYLPHENYLBORONIC ACID

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