|
| | 2,4-DINITROBENZOIC ACID Basic information |
| | 2,4-DINITROBENZOIC ACID Chemical Properties |
| Melting point | 176-180 °C (lit.) | | Boiling point | 351.93°C (rough estimate) | | density | 1.688 | | refractive index | 1.5300 (estimate) | | storage temp. | Store below +30°C. | | solubility | dioxane: 50 mg/mL, clear | | pka | 1.43(at 25℃) | | Water Solubility | 18.2g/L(25 ºC) | | BRN | 658650 | | CAS DataBase Reference | 610-30-0(CAS DataBase Reference) | | EPA Substance Registry System | Benzoic acid, 2,4-dinitro- (610-30-0) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | DG9140500 | | Hazard Note | Irritant | | TSCA | Yes | | HS Code | 29163990 |
| | 2,4-DINITROBENZOIC ACID Usage And Synthesis |
| Chemical Properties | pale yellow crystalline powder | | Uses | 2,4-Dinitrobenzoic acid was used in the spectrophotometric determination of diazepam in pure samples and in its pharmaceutical preparations. It was employed as chromophore probe for analysis of perfluorinated carboxylic acids in water by capillary zone electrophoresis. It can be used to produce 2,4-dinitro-benzoyl chloride. | | Uses | 2,4-Dinitrobenzoic acid can be used as a reactant:
- In decarboxylative C-N cross-coupling reactions.
- To synthesize Zwitterionic azaspirocyclic hydantoins by reacting with various carbodiimides via in situ intramolecular dearomatization reaction.
- To prepare 1-(2,4-dinitrophenyl)ethanone by condensation with dimethyl malonate and subsequent decarboxylation reaction.
It can also be used in the spectrophotometric determination of diazepam in pure samples and in its pharmaceutical preparations. In capillary zone electrophoresis, it can be employed as chromophore probe for the analysis of perfluorinated carboxylic acids in water. |
| | 2,4-DINITROBENZOIC ACID Preparation Products And Raw materials |
| Raw materials | Potassium dichromate-->2,4-Dinitrotoluene-->Benzoic acid, 2,4-dinitro-, phenyl ester-->Benzene,1,1'-(1,2-ethanediyl)bis(2,4-dinitro-)-->2,4-dinitrobenzoyl chloride-->2,4-Dinitrobenzaldehyde-->2 4-DINITROBENZYL ALCOHOL 97-->Phenol | | Preparation Products | 4-Nitroanthranilic acid-->1-BROMO-2,4-DINITROBENZENE-->2,4-DINITROBENZYL BROMIDE-->1-IODO-3,5-DINITROBENZENE-->4-Chlorophenol-->2,4-Dinitrophenol-->2,5-DINITROBENZOIC ACID-->3,4-Dinitrobenzoic acid-->4-Cyanophenol |
|
