ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Hydroxypyridine 2-Pyridinol-1-oxide

2-Pyridinol-1-oxide

2-Pyridinol-1-oxide Basic information
Product Name:2-Pyridinol-1-oxide
Synonyms:Pyridinium,1,2-dihydroxy-,1-hydroxide,inner salt;2-Hydorxy Pyridine-N-Oxide;2-HYDROXYPYRIDINE N-OXIDE 98%;2-HYDROXYPYRIDINE N-OXIDE 98+%;2-HYDROXYPRIDINE-N-OXIDE;2-Hydroxypyridine-N-oxide, 2-Pyridinol N-oxide, 1-Hydroxy-2-pyridone;HPNO;1-Hydroxy-2-pyridone, 2-Pyridinol N-oxide
CAS:13161-30-3
MF:C5H5NO2
MW:111.1
EINECS:236-100-8
Product Categories:Heterocycle-Pyridine series;Other Products;Pyridines, Pyrimidines, Purines and Pteredines;Pharm intermediate
Mol File:13161-30-3.mol
2-Pyridinol-1-oxide Structure
2-Pyridinol-1-oxide Chemical Properties
Melting point 147-152 °C
Boiling point 387.7±15.0 °C(Predicted)
density 1.111
vapor pressure 0.223Pa at 25℃
Fp 100 °C
storage temp. Inert atmosphere,2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
pkapK1:-0.62;pK2:5.97(0) (25°C)
color Off-White to Light Yellow
Water Solubility 331g/L
BRN 1422545
InChIKeyJVHZMYAXZUIZKS-UHFFFAOYSA-N
LogP-1.07 at 25℃
CAS DataBase Reference13161-30-3(CAS DataBase Reference)
NIST Chemistry Reference2-Pyridinol-1-oxide(13161-30-3)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 36/37/38-40
Safety Statements 26-36-22
WGK Germany 3
HS Code 29333990
MSDS Information
ProviderLanguage
SigmaAldrich English
2-Pyridinol-1-oxide Usage And Synthesis
Chemical PropertiesWeight 20% solution in water
Uses2-Pyridinol 1-oxide can be used:????
  • To fabricate gold electrodes for the electrochemical determination of europium using cyclic voltammetry.????????
  • To prepare polymeric nickel (II) complex of 2-hydroxypyridine-N-oxide.
  • In the synthesis of 1-methoxypyrid-4-one in the presence of sodium methoxide and methyl toluene-9-sulphonate.
DefinitionBactericidal agent related to aspergillic acid, made from pyridine-N-oxide.
General Description2-Pyridinol 1-oxide (HOPO) is a peptide coupling agent used as a subsititue for HOBt. It can form stable chelate complexes with transition metal ions.
2-Pyridinol-1-oxide Preparation Products And Raw materials
Raw materialsHydrochloric acid-->Acetic acid-->Hydrogen peroxide-->2-Methoxypyridine
Sulfasalazine 1-Hexadecylpyridinium bromide ETHYLENE OXIDE 2-Chloro-5-chloromethylpyridine Hydroxy silicone oil (Diethoxymethyl)diphenylphosphine oxide Iron oxide 2-(Hydroxymethyl)pyridine Zinc oxide NITRIC OXIDE Pyridine-N-oxide 2,3,4-Trihydroxybenzoic acid Chromium picolinate PYRIDINE-D5 2-Hydroxypyridine 2,5-Dimethylpyridine Magnesium oxide Propylene oxide
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