3,5-Dichlorophenylboronic acid

3,5-Dichlorophenylboronic acid Basic information
Product Name:3,5-Dichlorophenylboronic acid
Synonyms:AKOS BRN-0088;3,5-DICHLOROPHENYLBORONIC ACID;3,5-DICHLOROBENZENEBORONIC ACID;RARECHEM AH PB 0088;3,5-Dichlophenylboronic acid;3,5-Dichlorobenzeneboronicacid,98%;3,5-DICHLOROPHENYLBORONIC ACID 98%;3,5-Dichlorophenylboronic Acid (contains varying amounts of Anhydride)
CAS:67492-50-6
MF:C6H5BCl2O2
MW:190.82
EINECS:
Product Categories:Boronic Acid;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids and Derivatives;Boronic acids;Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Disubstituted Aryl Boronic Acids;Organometallic Reagents;Aryl;Organoborons;Substituted Boronic Acids;blocks;BoronicAcids;Fluorin-contained phenyl boronic acid series
Mol File:67492-50-6.mol
3,5-Dichlorophenylboronic acid Structure
3,5-Dichlorophenylboronic acid Chemical Properties
Melting point 315 °C
Boiling point 351.7±52.0 °C(Predicted)
density 1.47±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility soluble in Methanol
form powder to crystal
pka6.58±0.10(Predicted)
color White to Almost white
BRN 7581091
CAS DataBase Reference67492-50-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn,F
Risk Statements 36/37/38-22-19-11
Safety Statements 26-36-37/39-33-16
WGK Germany 3
HazardClass IRRITANT
HS Code 29319090
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
3,5-Dichlorophenylboronic acid Usage And Synthesis
Chemical Propertieswhite to off-white powder
Uses3,5-Dichlorobenzeneboronic Acid, is an intermediate for the synthesis of various pharmaceutical compounds including inhibitors. 3,5-Dichlorobenzeneboronic Acid was also found to facilitate the transport of various ribonucleosides in and out of liposomes (artificial cells).
Usessuzuki reaction
UsesReactant involved in:• ;Suzuki-Miyaura cross-coupling1,2• ;Trifluoromethylation3• ;Intramolecular aromatic carbenoid insertion of biaryldiazoacetates4• ;Cyanation for the synthesis of aromatic nitriles5• ;Lithiation of dihalophenyl dioxazaborocines for synthesis of functionalized dihalophenyl boronic acid6
3,5-Dichlorophenylboronic acid Preparation Products And Raw materials
Preparation Products3,5-Dichlorophenol-->3,3',5,5'-TETRACHLOROBIPHENYL-->1,3-dichloro-5-(3,3,3-trifluoroprop-1-en-2-yl)benzene-->3,5-Dichlorobenzophenone-->4,6-bis(3,5-dichlorophenyl)-2-methylpyrimidine-->4-(3,5-Dichlorophenyl)benzonitrile-->2-(3-3,5-DICHLOROPHENYL)-2,3-DIHYDRO-1H-NAPHTHO[1,8-DE][1,3,2]DIAZABORININE
2-(3,5-Dichloro-4-methoxyphenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane 3,5-Difluorophenylboronic acid 2-(Bromomethyl)-3,4,5-trichlorophenylboronic acid 3,4,5-Trichloro-2-methylphenylboronic acid 3,5-Dichlorophenylboronic acid 2-(3,5-Dichloro-4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane 3,5-DICHLORO-4-METHOXYBENZENEBORONIC ACID Ethyl 2-(Chlorosulfonyl)acetate 4-(BENZYLOXY)-3,5-DICHLOROPHENYLBORONIC ACID 2-(4-Benzyloxy-3,5-dichlorophenyl)-4,4,6-trimethyl-1,3,2-dioxaborinane 2-(4-Benzyloxy-3,5-dichlorophenyl)-5,5-dimethyl-1,3,2-dioxaborinane 3,5-Dichloro-2-methylphenylboronic acid 4-ETHOXY-3,5-DICHLOROPHENYLBORONIC ACID 3,5-Dimethylphenylboronic acid 2,6-Dichloro-4-(4,4,6-trimethyl-1,3,2-dioxaborinane-2-yl)phenol p-Dichlorobenzene (3,4,5-Trichlorophenyl)boronic acid 3,5-DICHLOROPHENYLBORONIC ACID, PINACOL ESTER

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