N-Trans-Feruloyltyramine

N-Trans-Feruloyltyramine Basic information
Product Name:N-Trans-Feruloyltyramine
Synonyms:N-Trans-Feruloyltyramine;(E)-3-(4-hydroxy-3-Methoxy-phenyl)-N-[2-(4-hydroxyphenyl)ethyl]prop-2-enaMide;2-Propenamide, 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]-, (2E)-;Moupinamide >=95% (LC/MS-ELSD);(2E)-3-(4-Hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)ethyl]acrylamide;N-trans-Feruloy-Tyramine;COX,Cyclooxygenase,Inhibitor,N trans Feruloyltyramine,NtransFeruloyltyramine,inhibit
CAS:66648-43-9
MF:C18H19NO4
MW:313.35
EINECS:
Product Categories:
Mol File:66648-43-9.mol
N-Trans-Feruloyltyramine Structure
N-Trans-Feruloyltyramine Chemical Properties
Melting point 138-140 °C(Solv: chloroform (67-66-3); methanol (67-56-1))
Boiling point 603.3±55.0 °C(Predicted)
density 1.248±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO and methan
pka9.83±0.31(Predicted)
form powder
color White
InChIKeyNPNNKDMSXVRADT-WEVVVXLNSA-N
Safety Information
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany 3
MSDS Information
N-Trans-Feruloyltyramine Usage And Synthesis
Chemical PropertiesSoluble in methanol, ethanol, DMSO and other organic solvents, derived from the Solanaceae plant Solanum torvum, which is used as a medicine with its roots; Physalis alkekengi L. var.francheti (Mast.) Makino , its dried perennial calyx or perennial calyx with fruit as a traditional Chinese medicine is included in various editions of Chinese pharmacopoeia. .
UsesAlfrutamide is a phenolic amides found in garlic and cocoa. Alfrutamide inhibits cyclooxygenases 1 and 2.
DefinitionChEBI: N-feruloyltyramine is a member of tyramines. It has a role as a metabolite.
Biological ActivityN-trans-Feruloyltyramine (N-feruloyltyramine), an alkaloid isolated from Piper nigru, is an inhibitor of COX1 and COX2 with antioxidant and anti-inflammatory activities.
target

COX-1

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COX-2

CYNARIN 4-Allylpyrocatechol 2,3,4,5-Tetracaffeoyl-D-Glucaric acid 1-Caffeoylquinic acid 6-Methoxysalicylic acid 3-O-GalloylMucic acid 2'-acetylacteoside CYNARIN 1,3,5-Tricaffeoylquinic acid Cynarin MacaMide IMpurity 2

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