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O-Desmethyl Gefitinib

O-Desmethyl Gefitinib Basic information
Product Name:O-Desmethyl Gefitinib
Synonyms: M523595;4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol;O-Desmethyl Gefitinib;Gefitinib O-Desmethyl Impurity;Gefitinib Impurity 13;O-DesmethylGefitinibmetabolite;Gefitinib impurity H;7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)aMino]-6-[3-(4-Morpholinyl)propoxy]-
CAS:847949-49-9
MF:C21H22ClFN4O3
MW:432.88
EINECS:
Product Categories:Intermediates & Fine Chemicals;Metabolites & Impurities;Various Metabolites and Impurities;Pharmaceuticals
Mol File:847949-49-9.mol
O-Desmethyl Gefitinib Structure
O-Desmethyl Gefitinib Chemical Properties
Melting point 117-120?C
storage temp. -20°C Freezer
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Yellow
Stability:Hygroscopic
Safety Information
Safety Statements 24/25
HS Code 29349990
MSDS Information
O-Desmethyl Gefitinib Usage And Synthesis
Chemical PropertiesYellow Solid
UsesO-Desmethyl Gefitinib-d8 is the isotope labelled analog of O-Desmethyl Gefitinib (D291680); a major metabolite of Gefitinib (G304000) which is an antineoplastic.
DefinitionChEBI: O-desmethyl Gefitinib is a member of quinazolines.
O-Desmethyl Gefitinib Preparation Products And Raw materials
3-(3-morpholinylpropoxy)-4-methoxybenzonitrile 4-Defluoro-4-hydroxy Gefitinib Gefitinib-d6 N-(3-chloro-4-fluorophenyl)-6 ,7-dimethoxyquinazolin-4-amine Gefitinib iMpurity O-Desmethyl Gefitinib-d6 4-methoxy-3-(3-morpholinopropoxy)-2-nitrobenzonitrile 6,7-Dimethoxy-3,4-dihydroquinazoline-4-one N-(3-chloro-4-fluorophenyl)-7 -methoxy-6-(3-morpholinopropoxy)-N-(3-morpholinopropyl)quinazolin-4-amine 2-aMino-4-Methoxy-5-(3-Morpholinopropoxy)benzaMide 3-Deschloro-4-Desfluoro-4-Chloro-3-Fluorogefitinib 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate Gefitinib Impurity 35 4-Methoxy-5-(3-Morpholinopropoxy)-2-nitrobenzaMide Gefitinib N-Oxide 4,4'-(propane-1,3-diyl)bismorpholine Gefitinib O-Methyl-D3 Gefitinib
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