Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a potent fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.
in vivo
Gatifloxacin hydrochloride (subcutaneous injection; 100 mg/kg; 3 times a day; 30 days) significantly decreases the number of lesions in mouse footpad with Nocardia brasiliensis .
< p>
Animal Model:
Female BALB/c mice with Nocardia brasiliensis in the right hind footpad
Dosage:
100 mg/kg
Administration:
Subcutaneous injection; 3 times a day; 30 days
Result:
Reduced the production of lesions in mice.
target
Topoisomerase II
36.7 μM ()
Gatifloxacinacid Preparation Products And Raw materials
