(R)-2-Amino-2-(4-fluorophenyl)ethanol Chemical Properties
Boiling point
287.4±25.0 °C(Predicted)
density
1.208±0.06 g/cm3(Predicted)
storage temp.
2-8°C(protect from light)
pka
12.48±0.10(Predicted)
Safety Information
HS Code
2922190090
MSDS Information
(R)-2-Amino-2-(4-fluorophenyl)ethanol Usage And Synthesis
Uses
(R)-2-Amino-2-(4-fluorophenyl)ethanol is used for synthesis of organic compounds.
Synthesis
To a stirred solution of lithium aluminium hydride (1.0 M in THF, 11.9 ml, 11.9 mmol) at 0℃ was added 4- (R)-fluorophenylglycine (1.0 g, 5.9 mmol) portion wise over 1 hour. The mixture was stirred at room temperature for 16 hours. Water (0.45 ml), 4 NNaOH (0.45 ml) and water (1.34 ml) was added to the mixture and the mixture was stirred for 10 minutes before being filtered. The filtrate was concentrated to give a yellow residue, (R)-2-Amino-2-(4-fluorophenyl)ethanol.
(R)-2-Amino-2-(4-fluorophenyl)ethanol Preparation Products And Raw materials
