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| | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Basic information |
| Product Name: | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- | | Synonyms: | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis-;4-((2,2'-bis(hydroxymethyl)-4'-(4-isocyanophenoxy)-[1,1'-biphenyl]-4-yl)oxy)benzonitrile;Crisaborole Diamer;4,4'-((2,2'-bis(hydroxymethyl)-[1,1'-biphenyl]-4,4'-diyl)bis(oxy))dibenzonitrile;Crisaborole Dimer ImpurityQ: What is
Crisaborole Dimer Impurity Q: What is the CAS Number of
Crisaborole Dimer Impurity | | CAS: | 2254541-79-0 | | MF: | C28H20N2O4 | | MW: | 448.47 | | EINECS: | | | Product Categories: | | | Mol File: | 2254541-79-0.mol | ![Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Structure](CAS/20200611/GIF/2254541-79-0.gif) |
| | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Chemical Properties |
| Boiling point | 702.3±60.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | pka | 13.95±0.10(Predicted) |
| | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Usage And Synthesis |
| Uses | Crisaborole Diamer Impurity is an impurity of Crisaborole (H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent. |
| | Benzonitrile, 4,4'-[[2,2'-bis(hydroxymethyl)[1,1'-biphenyl]-4,4'-diyl]bis(oxy)]bis- Preparation Products And Raw materials |
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