MAFENIDE ACETATE

MAFENIDE ACETATE Basic information
Product Name:MAFENIDE ACETATE
Synonyms:P-(AMINOMETHYL) BENZENESULFONAMIDE ACETATE;P-AMINOMETHYLBENZENESULFONAMIDE ACETATE SALT;ALPHA-AMINO-P-TOLUENSULFONAMIDE MONOACETATE;4-(AMINOMETHYL)-BENZENESULFOAMIDE MONOACETATE;4-HOMOSULFANILAMIDE ACETATE;4-HOMOSULFANILAMIDE ACETATE SALT;MAFENIDE;MAFENIDE ACETATE SALT
CAS:7761-27-5
MF:C9H14N2O4S
MW:246.28
EINECS:235-855-0
Product Categories:
Mol File:7761-27-5.mol
MAFENIDE ACETATE Structure
MAFENIDE ACETATE Chemical Properties
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
MAFENIDE ACETATE Usage And Synthesis
IndicationsMafenide (Sulfamylon) is a synthetic antibacterial agent related chemically, but not pharmacologically, to the sulfonamides. The drug appears to interfere with bacterial cellular metabolism and is not antagonized by PABA, pus, or serum. It is bacteriostatic against many gram-positive and gram-negative organisms, including staphylococci, streptococci, and Pseudomonas species. Mafenide is highly soluble and diffuses easily through an eschar. After percutaneous absorption, the drug is metabolized; it acts as a weak carbonic anhydrase inhibitor and may therefore cause systemic acidosis.
Mafenide is used primarily in the adjunctive treatment of second- and thirddegree burn wounds. It may cause severe pain on application, and active allergic contact sensitivity may develop.
MAFENIDE ACETATE Preparation Products And Raw materials
Mafenide acetate

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