Sulfacetamide sodium

Sulfacetamide sodium Basic information
Product Name:Sulfacetamide sodium
Synonyms:Sodium acetyl((4-aminophenyl)sulfonyl)amide;Sodium acetyl((4-aminophenyl);SULPHACETAMIDE SODIUM;SULFACETAMIDE SODIUM SALT;N-4-(AMINOBENZENESULFONYL)ACETAMIDE SODIUM SALT;albucide;albucidsoluble;almocetamide
CAS:127-56-0
MF:C8H9N2NaO3S
MW:236.22
EINECS:204-848-4
Product Categories:Used to treat conjunctivitis, sand holes and other eye infections;API;Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use)
Mol File:127-56-0.mol
Sulfacetamide sodium Structure
Sulfacetamide sodium Chemical Properties
Melting point 257 °C
storage temp. Keep in dark place,Inert atmosphere,Room temperature
Water Solubility Soluble in water
solubility DMF: 20 mg/mL; DMSO: 15 mg/mL; Ethanol: 1 mg/mL; PBS (pH 7.2): 5 mg/mL
form neat
color White to Almost white
Merck 14,8899
CAS DataBase Reference127-56-0
EPA Substance Registry SystemAcetamide, N-[(4-aminophenyl)sulfonyl]-, monosodium salt (127-56-0)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR 3249
WGK Germany 3
RTECS AC8480000
HS Code 2935.90.9500
HazardClass 6.1(b)
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
Sulfacetamide sodium Usage And Synthesis
DescriptionSulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC50 = 9.6 μM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid , which is required for the synthesis of folic acid.
UsesSulfacetamide Sodium Salt is an antibiotic that blocks synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. It can be used in biological study to explore topical application of benzoyl peroxide, antibiotics, sulfur and sodium sulfacetamide, azelaic acid for treatment of acne vulgaris in humans.
UsesSulfacetamide Sodium is an anti-biotic
DefinitionChEBI: An organic sodium salt that is the monosodium salt of sulfacetamide.
Brand nameBleph (Allergan); Cetamide (Alcon); Klaron (Sanofi Aventis); Ocusulf (MIZA); Sodium Sulamyd (Schering); Sulf (Novartis); Sulfacel (Optopics); Sulfair (Pharmafair); Sulten (Bausch & Lomb).
Sulfacetamide sodium Preparation Products And Raw materials
Raw materialsSulfanilamide
Preparation ProductsSulfacetamide
Sulfamic acid monosodium salt Sodium benzoate Sulfacetamide sodium Acesulfame SULFOACETIC ACID DISODIUM SALT Acetaminophen sodium Acetamide Sodium sulfate Sodium chloride 3,4'-DIAMINODIPHENYLMETHANE 4-Amino-benzenesulfonic acid monosodium salt Sodium citrate Sodium bicarbonate Sodium N-cyclohexylsulfamate Sodium chlorite Sodium amide 8-CHLOROADENOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT

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