ChemicalBook Product Catalog Organic Chemistry Organic fluorine compound Fluorophenyl boronic acid series 3,5-Difluorophenylboronic acid

3,5-Difluorophenylboronic acid

3,5-Difluorophenylboronic acid Basic information
Product Name:3,5-Difluorophenylboronic acid
Synonyms:3,5-DIFLUOROBENZENEBORONIC ACID;3,5-DIFLUOROPHENYLBORONIC ACID;AKOS BRN-0091;RARECHEM AH PB 0167;Boronic acid, (3,5-difluorophenyl)- (9CI);3,5-Difluorobenzeneboronic acid 98%;3,5-Difluorobenzeneboronicacid98%;3,5-DIFLUOROPHENYLBORONIC ACID 98%
CAS:156545-07-2
MF:C6H5BF2O2
MW:157.91
EINECS:605-060-7
Product Categories:Liquid crystal intermediates;Aryl Boronic Acids;Boronic Acids and Derivatives;Chemical Synthesis;Disubstituted Aryl Boronic Acids;Organometallic Reagents;Fluorin-contained phenyl boronic acid series;Substituted Boronic Acids;Boronic Acid;Aryl;B (Classes of Boron Compounds);Boronic Acids;Boronic Acids;Boronic Acids and Derivatives;HALIDE;blocks;BoronicAcids;FluoroCompounds;Organoborons;intermediate
Mol File:156545-07-2.mol
3,5-Difluorophenylboronic acid Structure
3,5-Difluorophenylboronic acid Chemical Properties
Melting point 210-217 °C (lit.)
Boiling point 266.9±50.0 °C(Predicted)
density 1.35±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka6.46±0.10(Predicted)
form powder
color White to Orange to Green
BRN 6800882
CAS DataBase Reference156545-07-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi,Xn,F
Risk Statements 36/37/38-20-19-11-22
Safety Statements 26-36-33-16-37/39
WGK Germany 3
HazardClass IRRITANT
HS Code 29163990
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
3,5-Difluorophenylboronic acid Usage And Synthesis
Chemical PropertiesWhite to beige-yellowish powder
UsesReactant involved in:• ;Synthesis of honokiol analogs as angiogenesis inhibitors1• ;Homo-coupling reactions2• ;Suzuki-Miyaura cross-coupling reactions3• ;Enantioselective borane reduction of trifluoroacetophenone4
Usessuzuki reaction
Uses3,5-Difluorophenylboronic Acid is used in the synthesis of N-thiazol-2-yl-benzamides as glucokinase (GK) activators for treatment of type 2 diabetes mellitus (T2DM).
UsesIntermediates of Liquid Crystals
3,5-Difluorophenylboronic acid Preparation Products And Raw materials
Preparation Products3-(3,5-DIFLUOROPHENYL)PICOLINALDEHYDE-->3,5-DIFLUOROBENZOPHENONE-->4-(3,5-Difluorophenyl)benzonitrile-->3',5'-Difluoro-biphenyl-3-aMine-->3-BIPHENYL-3',5'-DIFLUORO-ACETIC ACID -->3-(3,5-DIFLUOROPHENYL)OXETANE
3,4,5-TRIFLUOROPHENYLBORONIC ACID, PINACOL ESTER 3,5-Difluorophenylboronic acid Ethyl 2-(Chlorosulfonyl)acetate Transfluthrin Ascoric Acid 4-BROMO-3,5-DIFLUOROBENZENEBORONIC ACID Folic acid Phenylboronic acid (3,5-DIFLUORO-2-METHOXYPHENYL)BORONIC ACID, 97 3,5-Dimethylphenylboronic acid 4-Fluorobenzeneboronic acid 3,4,5-Trifluorophenylboronic acid 2,3,4,5,6-PENTAFLUOROBENZENEBORONIC ACID Florfenicol 3-Fluorophenylboronic acid EPA 1,3-Difluorobenzene Citric acid
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