N-ACETYLTHIOUREA

N-ACETYLTHIOUREA Basic information
Product Name:N-ACETYLTHIOUREA
Synonyms:LABOTEST-BB LT00000307;1-Acetyl-2-thiocarbamide;1-acetyl-2-thio-ure;acetamide,n-(aminothioxomethyl)-;Acetothiourea;1-ACETYLTHIOUREA;1-ACETYL-2-THIOUREA;THIOCARBAMYL ACETAMIDE
CAS:591-08-2
MF:C3H6N2OS
MW:118.16
EINECS:209-699-9
Product Categories:Organic Building Blocks;Sulfur Compounds;Thioureas
Mol File:591-08-2.mol
N-ACETYLTHIOUREA Structure
N-ACETYLTHIOUREA Chemical Properties
Melting point 165-169 °C(lit.)
density 1.240 (estimate)
refractive index 1.7000 (estimate)
storage temp. Store below +30°C.
solubility 12.8g/l
pka11.24±0.70(Predicted)
form Crystalline Powder
color Pale cream
PH6.0 (173g/l, H2O, 20℃)
BRN 969960
CAS DataBase Reference591-08-2(CAS DataBase Reference)
EPA Substance Registry System1-Acetyl-2-thiourea (591-08-2)
Safety Information
Hazard Codes T
Risk Statements 25
Safety Statements 36/37/39-45
RIDADR UN 2811 6.1/PG 2
WGK Germany 3
RTECS YR7700000
Hazard Note Highly Toxic
TSCA Yes
HazardClass 6.1
PackingGroup II
HS Code 2930909899
Hazardous Substances Data591-08-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
N-ACETYLTHIOUREA Usage And Synthesis
Chemical Propertieswhite crystalline powder
Chemical Properties1-Acetyl-2-thiourea is a white crystalline solid; forming needles
UsesN-Acetylthiourea is a derivative of Thiourea (T375450)
DefinitionChEBI: N-acetylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an acetyl group. It is a member of acetamides and a member of thioureas. It is functionally related to a thiourea.
General DescriptionWhite crystalline solid. Noncombustible, but decomposes with heating.
Air & Water ReactionsSlightly soluble in water, soluble in hot water. Hydrolysis occurs rapidly with strong acid/base media.
Reactivity ProfileN-ACETYLTHIOUREA is incompatible with strong oxidizing agents, strong acids and strong bases. Decomposes when heated to give toxic oxides of sulfur and nitrogen.
Health HazardTOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire HazardNon-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.
Potential ExposureStudied as possible rodenticide; used in organic synthesis.
ShippingUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
Purification MethodsRecrystallise the thiourea from AcOH; the solid is washed with Et2O and dried in air then at 100o. [Zahradnik Collect Czech Chem Commun 24 3678 1959, Beilstein 3 IV 354.]
IncompatibilitiesIncompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
Waste DisposalConsult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal.
N-ACETYLTHIOUREA Preparation Products And Raw materials
Raw materialsAcetyl chloride-->Thiourea
Preparation ProductsACETYLUREA
1-ACETYL-2-THIOHYDANTOIN 3-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROQUINAZOLIN-4-ONE 5,5-DIPHENYL-2-THIOHYDANTOIN AURORA 1039 2-THIOOROTIC ACID 2-Thiohydantoin Methylthiouracil 2-Mercapto-4-hydroxy-5,6-diaminopyrimidine 5-METHYL-2-THIOURIDINE 2-Thiobarbituric acid 1-BENZOYL-3-PHENYL-2-THIOUREA 1,3-DIETHYL-2-THIOBARBITURIC ACID 2-Thiouracil 2-THIO-6-AZAURIDINE AURORA 1921 MEROCYANINE 540 6-AZA-2-THIOTHYMINE Propylthiouracil

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