ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards 5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE

5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE

5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE Basic information
Product Name:5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE
Synonyms:5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE;SALOR-INT L233021-1EA;3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE;3-(4-Methylphenyl)-5-(trifluoromethyl)pyrazole;3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole;Celecoxib-010-1;Celecoxib Impurity 27;5-(4-Methylphenyl)-3-(trifluoromethyl)py
CAS:219986-64-8
MF:C11H9F3N2
MW:226.2
EINECS:
Product Categories:
Mol File:219986-64-8.mol
5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE Structure
5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE Chemical Properties
Melting point 155.3-156.8 °C
Boiling point 344.2±42.0 °C(Predicted)
density 1.284±0.06 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka10.08±0.10(Predicted)
color White to Pale Yellow
Stability:Hygroscopic
Safety Information
MSDS Information
5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE Usage And Synthesis
Uses3-Trifluoromethyl-5-(p-tolyl)-1H-pyrazole is an impurity of cyclooxygenase-2 (COX-2) inhibitor Celecoxib (C251000).
5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE Preparation Products And Raw materials
5-(TRIFLUOROMETHYL)-3-P-TOLYL-1H-PYRAZOLE 3-{2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOL-4-YL}PHENYL ACETATE 4-(4-METHOXYPHENYL)-2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE 2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE-4-CARBOXYLIC ACID 4-{2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOL-4-YL}PHENYL ACETATE 2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-4-(4-NITROPHENYL)-1,3-THIAZOLE 4-{2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOL-4-YL}PHENYL ACETATE 2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE-4-CARBOXYLIC ACID 3-{2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOL-4-YL}PHENOL 5-(4-ETHYL-PHENYL)-3-TRIFLUOROMETHYL-1H-PYRAZOLE 4-(4-CHLOROPHENYL)-2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE 4-METHYL-6-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]PYRIMIDIN-2-AMINE 4-(4-FLUOROPHENYL)-2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE 4-(4-CHLOROPHENYL)-2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE 4-(4-METHOXYPHENYL)-2-[3-(4-METHYLPHENYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE Celecoxib 4-(4-FLUOROPHENYL)-2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-1,3-THIAZOLE 2-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]-4-PHENYL-1,3-THIAZOLE
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