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| | ERYTHROSIN B Basic information |
| | ERYTHROSIN B Chemical Properties |
| Melting point | 142~144℃ | | density | 0.98 | | vapor pressure | 0Pa at 25℃ | | Fp | 285℃ | | storage temp. | room temp | | solubility | 100g/l | | Colour Index | 45430 | | pka | 4.1(at 25℃) | | form | Fine Powder | | color | Deep red to brown | | PH | 6-7 (10g/l, H2O, 20℃) | | PH Range | 0(yellow)-3.6(red) | | Water Solubility | Soluble in water | | λmax | 525nm | | Merck | 14,3693 | | BRN | 1443945 | | Stability: | Stable. Incompatible with strong oxidizing agents. | | Biological Applications | Detecting gene expression,phosphoproteins,protease,stress biomarkers; treating age-related macular degeneration,arteriosclerosis,bone metabolic diseases,burns,cancer,diabetes,human immunodeficiency virus infection,obesity | | Major Application | color filter, light emitting diodes, nanosensors, imaging materials, inks, paints, colored bubbles, detergents, cleaners, cosmetics, oral care agent, hair dyes, antiseptic, treatment of burns, diabetes, obesity, cancer, viral diseases, radio chemotheray, photodynamic therapy | | InChIKey | RAGZEDHHTPQLAI-UHFFFAOYSA-L | | LogP | -1.163 at 25℃ | | CAS DataBase Reference | 16423-68-0 | | EPA Substance Registry System | Erythrosine B (16423-68-0) |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 36 | | WGK Germany | 3 | | RTECS | LM5950000 | | HS Code | 32129000 | | Hazardous Substances Data | 16423-68-0(Hazardous Substances Data) | | Toxicity | LD50 in male, female mice, male, female rats (g/kg): 0.40, 0.32, 0.34, 0.37 i.p.; 6.7, 6.9, 7.4, 6.8 orally (Butterworth); LD50 in mice, rats (mg/kg): 2558, 2891 orally (Yankell) |
| | ERYTHROSIN B Usage And Synthesis |
| Description | FD & C Red No. 3 is principally the disodium salt of the monohydrate of 9(ocarboxyphenyl)-6-hydroxy-2,4,5,7-tetraiodo-3H- xanthen-3-one.
The colorant is a brown powder that dissolves in water to give a solution red at neutrality, with a yellow-brown precipitate in acid, and with a red precipitate in base. When dissolved in concentrated sulfuric acid, it yields a brown-yellow solution that evolves iodine and a precipitate of the free acid when heated.
FD & C Red No. 3 is used in dietary supplements, confectionery products, dairy products, cherries, jellies, jams, dessert powders, canned fruit and vegetable products, fish products, condiment sauces and bakery goods.1
. | | Chemical Properties | red to brown powder | | Uses | antibacterial | | Uses | Erythrosine B is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products. | | Uses | Biological stain; color additive. | | Uses | Erythrosin B (FD&C Red #3) is a colorant. It is not recommended for use below ph 5.0, being insoluble at ph 3–5 but being stable at ph 7 and 8. It has a solubility in water of 9 g/100 ml at 25°c. It has fair stability to oxidation and poor to fair stability to light, while having good stability in 10% sugar systems. It has exceptional clarity and brilliance, having a bluish pink hue with very good tinctorial strength. It has poor compatibility with food components and is used in candies and confections as well as cherry dyeing. The common name is erythrosine. | | Preparation | fluorescent element (C.I. Acid Yellow 73, C.I. 45350) or ethanol in aqueous solution of the four iodine, then into sodium salt. | | Definition | ChEBI: An organic sodium salt that is the disodium salt of 2-(2,4,5,7-tetraiodo-6-oxido-3-oxo-8a,10a-dihydroxanthen-9-yl)benzoic acid. | | General Description | Erythrosin B (C.I. 45430)for microscopy Certistain?, is a dry dye for microscopy that is often used as a counterstain, vizualising proteins, connective tissues, fibers and keratin in sample material of human origin. Depending on user requirements and personal preferences, it can be used for the preparation of the commonly used aqueous or alcoholic Erythrosin B staining solutions. As the dye belongs to the portfolio of Certistain? dyes, it is chemically analyzed according to strict specifications before release (CE marked and IVD product) and a high staining quality, with reliable staining results is guaranteed. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage. | | Flammability and Explosibility | Notclassified | | Biochem/physiol Actions | Erythrosin B, also called as eosin B, is a xanthene dye. It belongs to the family of fluorescein dyes. Erythrosin B is an artificial food dye that induces hyperkinesis when swallowed by susceptible children. It plays a major role in inhibiting dopamine uptake and high affinity 3H-ouabain binding and ion transport in synaptosomes from rat caudate nucleus. | | storage | Room temperature | | Properties and Applications | blue light pink. Soluble in water is cherry red, no fluorescence. The strong sulfuric acid is palm in light yellow, diluted into palm yellow light precipitation. In water solution to join sodium hydroxide to create soluble red precipitate.
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| | ERYTHROSIN B Preparation Products And Raw materials |
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