ChemicalBook Product Catalog Pharmaceutical intermediates Heterocyclic compound Pyridine compound Methylpyridine 3-Picolyl chloride hydrochloride

3-Picolyl chloride hydrochloride

3-Picolyl chloride hydrochloride Basic information
Product Name:3-Picolyl chloride hydrochloride
Synonyms:3-pyridylmethylchloridehydrochloride;nci-c03838;3-(CHLOROMETHYL)PYRIDINE HYDROCHLORIDE;3-(CHLOROMETHYL)-PYRIDINIUM CHLORIDE;Rupatadine impurity 10;Pyridine,3-(chloromethyl)-, hydrochloride (1:1);3-PICOLYL CHLORIDE HYDROCHLORIDE;3-Picolyl chloride HCl (65% in water)
CAS:6959-48-4
MF:C6H7Cl2N
MW:164.03
EINECS:230-150-4
Product Categories:Heterocycle-Pyridine series;Pyridinium Compounds;blocks;Pyridines;Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Heterocycles
Mol File:6959-48-4.mol
3-Picolyl chloride hydrochloride Structure
3-Picolyl chloride hydrochloride Chemical Properties
Melting point 137-143 °C(lit.)
storage temp. Inert atmosphere,2-8°C
form Crystalline Needles or Powder
color White to beige
Water Solubility >=10 g/100 mL at 19 ºC
Sensitive Hygroscopic
BRN 3689156
CAS DataBase Reference6959-48-4(CAS DataBase Reference)
EPA Substance Registry System3-(Chloromethyl)pyridine hydrochloride (6959-48-4)
Safety Information
Hazard Codes Xn,C,T
Risk Statements 22-36/37/38-45-20/21/22-34
Safety Statements 26-36-53-45-36/37/39
RIDADR 2811
WGK Germany 3
RTECS US7000000
F 3-10
Hazard Note Corrosive
HazardClass 8
PackingGroup III
HS Code 29333999
Hazardous Substances Data6959-48-4(Hazardous Substances Data)
MSDS Information
ProviderLanguage
3-Picolyl chloride hydrochloride English
SigmaAldrich English
ACROS English
ALFA English
3-Picolyl chloride hydrochloride Usage And Synthesis
Chemical PropertiesWhite to pale brown solid
Uses3-(Chloromethyl)pyridine Hydrochloride has been used as a reactant for the synthesis of (E)-3-((1H-Indazol-6-yl)methylene)indolin-2-one derivatives as Polo-like kinase 4 (PLK4) inhibitors.
General DescriptionYellow powder or yellow-tan solid with an irritating odor.
Air & Water ReactionsHygroscopic. Water soluble.
Reactivity Profile3-Picolyl chloride hydrochloride is incompatible with strong oxidizing agents and strong bases.
Fire HazardFlash point data for 3-Picolyl chloride hydrochloride are not available; however, 3-Picolyl chloride hydrochloride is probably combustible.
Safety ProfileSuspected carcinogen with experimental carcinogenic data. Poison by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and Cl-.
NICOTINOYL CHLORIDE HYDROCHLORIDE, [CARBONYL-14C] 2,5-DICHLOROPYRIDINE-3-CARBONYL CHLORIDE 3-Picolyl chloride hydrochloride 2,3-DICHLOROPYRIDINE-5-CARBONYL CHLORIDE 2-CHLORO-3-(CHLOROMETHYL)-7-METHYLQUINOLINE 2-[(4-CHLOROPHENYL)THIO]PYRIDINE-3-CARBONYL CHLORIDE 4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBONYL CHLORIDE NICOTINYL CHLORIDE HYDROCHLORIDE 2,4-DICHLORO-3-DICHLOROMETHYLQUINOLINE 5-CHLOROMETHYL-2,2,8-TRIMETHYL-4H-[1,3]DIOXINO-[4,5-C]PYRIDINE HYDROCHLORIDE 2-Chloronicotinyl chloride 2-(4-CHLOROPHENOXY)PYRIDINE-3-CARBONYL CHLORIDE 5-(2-THIENYL)NICOTINOYL CHLORIDE HYDROCHLORIDE 2,6-dichloro-3-(trichloromethyl)pyridine 2-CHLORO-5-[CHLORO(DIFLUORO)METHYL]PYRIDINE 6-CHLORONICOTINOYL CHLORIDE 2-Chloro-5-trichloromethylpyridine 2-CHLORO-3-TRICHLOROMETHYLPYRIDINE
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