Halazone

Halazone Basic information
Product Name:Halazone
Synonyms:4-(N,N-Dichlorosulfamoyl)benzoic acid;4-(DICHLOROSULFAMOYL)BENZOIC ACID;HALAZONE;4-dichlorosulphamoylbenzoic acid;P-(N,N-dichlorosulfamyl)benzoic acid*minimum 70%;4-(N,N-Dichlorosulfamyl)BenzoicAcid70%;p-Sulfondichloraminobenzoic acid;PARA-SULPHONEDICHLORAMIDOBENZOICACID
CAS:80-13-7
MF:C7H5Cl2NO4S
MW:270.09
EINECS:201-253-1
Product Categories:
Mol File:80-13-7.mol
Halazone Structure
Halazone Chemical Properties
Melting point 195°C (rough estimate)
Boiling point 437.0±47.0 °C(Predicted)
density 1.5426 (rough estimate)
refractive index 1.6000 (estimate)
storage temp. Store at -20°C,unstable in solution, ready to use.
solubility Soluble in DMSO
pka3.29±0.10(Predicted)
form neat
Merck 14,4590
Stability:Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
CAS DataBase Reference80-13-7(CAS DataBase Reference)
NIST Chemistry ReferenceBenzoic acid, p-(dichlorosulfamoyl)-,(80-13-7)
EPA Substance Registry SystemHalazone (80-13-7)
Safety Information
RIDADR 1479
WGK Germany 3
RTECS DG8050000
HazardClass 5.1
PackingGroup III
MSDS Information
ProviderLanguage
4-(N,N-Dichlorosulfamoyl)benzoic acid English
SigmaAldrich English
Halazone Usage And Synthesis
Chemical Propertieswhite powder
OriginatorClordiapenser,Molteni Farmaceutici SpA.
UsesWater disinfectant.
Usesantiinfectant
Manufacturing Process20 kg p-aminosulfonyl benzoic acid was mixed with 400 L 0.5 N NaOCl. After an acidification with 100 L 1 N acetic acid, a precipitate dropped out. It was filtered off, washed and dried. The obtained 4-((dichloroamino)sulfonyl) benzoic acid had MP: 203°C.
Therapeutic FunctionAntiseptic, Antiseptic
General Descriptionp-Dichlorosulfamoylbenzoic acid is a white, crystalline,photosensitive compound with a faint chlorine odor.Halazone is only slightly soluble in water at pH 7 but becomesvery soluble in alkaline solutions. The sodium salt ofhalazone is used to disinfect drinking water.
General DescriptionFine white powder with an odor of chlorine.
Air & Water ReactionsInsoluble in water.
Fire HazardFlash point data for Halazone are not available, but Halazone is probably combustible.
Halazone Preparation Products And Raw materials
Raw materialsCarzenide-->Sodium hypochlorite
Docetaxel Ciprofloxacin hydrochloride FERROUS SULFATE Levofloxacin hydrochloride Pidotimod Halazone DICHLORAMINE T DICHLORAMINE B N-Chloro-p-toluenesulfonamide TEREPHTHALIC DIHYDRAZIDE Diethylene glycol dibenzoate P-DICHLOROAMINOSULFOBENZOIC ACID SODIUM SALT 3,5-Dihydroxybenzoic acid Terephthalic acid BENZOICACID Carzenide

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