N-Acetyl-DL-phenylalanine

N-Acetyl-DL-phenylalanine Basic information

Product Name:	N-Acetyl-DL-phenylalanine
Synonyms:	N-ALPHA-ACETYL-DL-PHENYLALANINE;N-ACETYL-DL-PHENYLALANINE;n-acetyl-dl-phenylalaninecrystalline;n-acetylphenylalanine;2-ACETYLAMINO-3-PHENYL-PROPIONIC ACID;AC-DL-PHE-OH;AC-DL-PHENYLALANINE;DL-2-(Acetylamino)-3-phenylpropanoic acid
CAS:	2901-75-9
MF:	C11H13NO3
MW:	207.23
EINECS:	220-793-9
Product Categories:	chiral
Mol File:	2901-75-9.mol

N-Acetyl-DL-phenylalanine Chemical Properties

Melting point	152.0 to 156.0 °C
Boiling point	453.9±38.0 °C(Predicted)
density	1.199±0.06 g/cm3(Predicted)
RTECS	SQ7321132
storage temp.	Inert atmosphere,Store in freezer, under -20°C
form	Powder
pka	3.56±0.10(Predicted)
color	Off-white
λmax	280nm(lit.)
CAS DataBase Reference	2901-75-9(CAS DataBase Reference)

Safety Information

WGK Germany	3
HS Code	2924.29.7790

MSDS Information

Provider	Language
SigmaAldrich	English

N-Acetyl-DL-phenylalanine Usage And Synthesis

Originator	Afalanine ,Sankyo
Uses	N-Acetyl-DL-phenylalanine is an antidepressant, used to prevent kidney damage.
Definition	ChEBI: The N-acetyl derivative of phenylalanine.
Manufacturing Process	The phenylalanine was dispersed in water. A 1 N aqueous solution of sodium hydroxide was slowly added to this dispersion, and the pH of the solution reached a value of 7-8. Then acetylbromide was dissolved in this solution, to give a Nacetylphenylalanine.
Therapeutic Function	Antidepressant
Synthesis Reference(s)	Tetrahedron Letters, 31, p. 243, 1990 DOI: 10.1016/S0040-4039(00)94382-X

N-Acetyl-DL-phenylalanine Preparation Products And Raw materials

Raw materials

Sodium hydroxide-->Acetyl bromide-->L-Phenylalanine-->2-ACETAMIDO-3-PHENYLACRYLIC ACID-->(4Z)-2-Methyl-4-(phenylmethylidene)-4,5-dihydro-1,3-oxazol-5-one-->Phenylacetaldehyde-->carbon monoxide-->DL-Phenylalanine-->Styrene oxide-->Acetamide-->Acetic anhydride-->Potassium thioacetate

N-Acetyl-DL-phenylalanine Phenprobamate N-Acetyl-DL-phenylalanine 4-nitrophenyl ester,ACETYL-DL-PHENYLALANINE 4-NITROPHENYL ESTER,N-ACETYL-DL-PHENYLALANINE P-NITROPHENYL ESTER N-Acetyl-L-phenylalanine AC-DL-PHE-BETA-NAPHTHYL ESTER AC-DL-PHE-PNA N-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-DL-phenylalanine Acetylacetone N-Acetyl-DL-phenylalanine methyl ester Ethyl 2-(Chlorosulfonyl)acetate L-Phenylalanine DL-Phenylalanine DL-Malic acid Acetyl chloride trans-Cinnamic acid phosphoric acid N-ACETYL-DL-PHENYLALANINE 100MG [R] N-ALPHA-ACETYL-DL-PHENYLALANINE,ACETYL-DL-PHENYLALANINE,AC-DL-PHE-OH

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