DIBENZYL DIETHYLPHOSPHORAMIDITE

DIBENZYL DIETHYLPHOSPHORAMIDITE Basic information
Product Name:DIBENZYL DIETHYLPHOSPHORAMIDITE
Synonyms:Bis(benzyloxy)(diethylaMino)phosphine;Dibenzyl (DiethylaMido)phosphite;DibenzyloxydiethylaMinophosphine;N,N-Diethyl-phosphoraMidous Acid Bis(phenylMethyl) Ester;DIBENZYL DIETHYLPHOSPHORAMIDITE;DIBENZYL N,N-DIETHYLPHOSPHORAMIDITE;DIBENZYL-N,N-DIETHYLPHOSPHOROAMIDITE;DIBENZYL DIETHYLPHOSPHORAMIDITE, TECH., 85%
CAS:67746-43-4
MF:C18H24NO2P
MW:317.36
EINECS:
Product Categories:Phospholipids - 13C & 2H;Regant series;Phosphorylating and Phosphitylating Agents;OLED materials,pharm chemical,electronic
Mol File:67746-43-4.mol
DIBENZYL DIETHYLPHOSPHORAMIDITE Structure
DIBENZYL DIETHYLPHOSPHORAMIDITE Chemical Properties
Boiling point 131-132 °C(Press: 0.0001 Torr)
density 1.06 g/mL at 25 °C(lit.)
vapor pressure 0.71 psi ( 55 °C)
refractive index n20/D 1.545(lit.)
Fp 95 °F
storage temp. 2-8°C
solubility Soluble in chloroform.
pka4.01±0.70(Predicted)
form Oil
color Clear Colourless to Pale Yellow
Sensitive Moisture Sensitive
BRN 4189915
Stability:Light Sensitive
CAS DataBase Reference67746-43-4
Safety Information
Hazard Codes Xi
Risk Statements 10-36/37/38
Safety Statements 16-26-37/39
RIDADR UN 1993 3/PG 3
WGK Germany 3
10-21
HazardClass 3.2
PackingGroup III
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
DIBENZYL DIETHYLPHOSPHORAMIDITE Usage And Synthesis
Chemical PropertiesClear Colourless Liquid
UsesDibenzyl diethylphosphoramidite is a useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters as well as dibenzyl glycosyl phosphites, which can easily be converted to glycosyl phosphates or used in glycosylation reagents in oligosaccharide synthesis.
UsesDibenzyl N,N-diethylphosphoramidite may be used:
  • as phosphitylating reagent in the synthesis of glycosyl phosphites and phosphates
  • for phosphorylating the alcohols
  • in the preparation of 6-dibenzylphosphate-1,3,5-tri-O-PMB-myo-inositol
General DescriptionDibenzyl N,N-diethylphosphoramidite is repoted to be suitable reagent for the efficient 1H-tetrazole-catalyzed ′phosphite-triester′ phosphorylation of the protected serine derivatives.
DIBENZYL DIETHYLPHOSPHORAMIDITE Preparation Products And Raw materials
DIBENZYL DIETHYLPHOSPHORAMIDITE DIBENZYL DIISOPROPYLPHOSPHORAMIDITE BIS[1-(2-NITROPHENYL)ETHYL] N,N-DIISOPROPYLPHOSPHORAMIDITE DIBENZYL N,N-DIMETHYLPHOSPHORAMIDITE Di-p-Chlorobenzyl N,N-Diisopropylphosphoramidite

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