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| | 135270-10-9 Basic information |
| Product Name: | 135270-10-9 | | Synonyms: | Efinaconazole Impurity 5;(2S,3S)-2-(2,4-difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane;1-(((2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole;Efinaconazole Related Impurity 5;Efinaconazole Impurity 20;1H-1,2,4-Triazole, 1-[[(2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]- (9CI);1-[[(2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiranyl]methyl]-1H-1,2,4-Triazole;1-(((2S,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity) | | CAS: | 135270-10-9 | | MF: | C12H11F2N3O | | MW: | 251.23 | | EINECS: | | | Product Categories: | | | Mol File: | 135270-10-9.mol |  |
| | 135270-10-9 Chemical Properties |
| Boiling point | 371.6±52.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | pka | 2.75±0.10(Predicted) |
| | 135270-10-9 Usage And Synthesis |
| Uses | (2S,3S)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of (2S,3R)-Efinaconazole (E435085); the 2S,3R-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis. |
| | 135270-10-9 Preparation Products And Raw materials |
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