ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)-

D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)-

D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)- Basic information
Product Name:D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)-
Synonyms:D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)-;Canagliflozin Impurity A;Defluoro-Canagliflozin;(2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(4-methyl-3-((5-phenylthiophen-2-yl)methyl)phenyl)tetrahydro-2H-pyran-3,4,5-triol;Canagliflozin Desfluoro Impurity;Canagliflozin Desfluoro Imp;Cagliflozin Defluoro Impurity;Desfluoro CanagliflozinQ: What is Desfluoro Canagliflozin Q: What is the CAS Number of Desfluoro Canagliflozin Q: What is the storage condition of Desfluoro Canagliflozin Q: What are the applications of Desfluoro Canagliflozin
CAS:842133-16-8
MF:C24H26O5S
MW:426.53
EINECS:
Product Categories:
Mol File:842133-16-8.mol
D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)- Structure
D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)- Chemical Properties
Boiling point 645.1±55.0 °C(Predicted)
density 1.326±0.06 g/cm3(Predicted)
pka13.34±0.70(Predicted)
Safety Information
MSDS Information
D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)- Usage And Synthesis
UsesDefluoro-Canagliflozin is an impurity of Canagliflozin (C175190), a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
D-Glucitol, 1,5-anhydro-1-C-[4-Methyl-3-[(5-phenyl-2-thienyl)Methyl]phenyl]-, (1S)- Preparation Products And Raw materials
Canagliflozin Furanose Impurity Pioglitazone hydrochloride Canagliflozin Impurity 11 2-(4-fluorophenyl)-5-(2-Methylbenzyl)thiophene Canagliflozin Impurity 56 Canagliflozin Impurity 53 Canagliflozin Impurity 14 Canagliflozin Impurity 33 Canagliflozin-10 Saxagliptin Canagliflozin Impurity 29 Canagliflozin Dimer Impurity 2 2-(1,2-dihydroxyethyl)-5-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydrofuran-3,4-diol Canagliflozin Impurity 20 Canagliflozin Impurity 22 (2R,3R,4R,5S,6R)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (3R,4S,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)-6-(hydroxyMethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol Canagliflozin Impurity 49
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