(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine

(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Basic information
Product Name:(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine
Synonyms:(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine;Fosaprepitant Impurity 28;Aprepitant Impurity SM3FDY1-1;Aprepitant M2 Metabolite 3-Epimer;Morpholine, 2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-, (2R,3R)-;Aprepitant M2 metabolite (1R, 2R, 3R)-isomer
CAS:380499-06-9
MF:C20H18F7NO2
MW:437.35
EINECS:
Product Categories:
Mol File:380499-06-9.mol
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Structure
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Chemical Properties
Boiling point 387.9±42.0 °C(Predicted)
density 1.37±0.1 g/cm3(Predicted)
pka6.93±0.60(Predicted)
Safety Information
MSDS Information
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Usage And Synthesis
(2R,3R)-2-[(1R)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine Preparation Products And Raw materials
Preparation Products(R,R,R)-Aprepitant
Benzyl dihydrogen phosphate Aprepitant 1,1,1-Trimethoxy-2-chloroethane (S)-2-((R)-1-(3,5-bis(trifluoroMethyl)phenyl)ethoxy)-4-benzylMorpholin-3-one 5-(hydroxymethyl)-1,2-dihydro-1,2,4-triazol-3-one Fosaprepitant Impurity 5 Aprepitant 4-BENZYL-2-HYDROXY-MORPHOLIN-3-ONE [2R-[2aR*),3a]-2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine (2R,3S)-2-[(1S)-1-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)Morpholine hydrochloride ent-Aprepitant 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethyl Acetate Aprepitant Impurity 15 Fosaprepitant Impurity 6 Aprepitant 2-(2-(4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol Aprepitant Aprepitant Impurity 19

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