5-IODO-1,3-DIMETHYLURACIL

5-IODO-1,3-DIMETHYLURACIL Basic information
Product Name:5-IODO-1,3-DIMETHYLURACIL
Synonyms:5-IODO-1,3-DIMETHYLURACIL;5-IODO-1,3-DIMETHYLURACIL, 99%%;5-Iodo-1,3-dimethylpyrimidine-2,4-dione;5-Iodo-1,3-diMethylpyriMidine-2,4(1H,3H)-dione;5-Iodo-1,3-dimethyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 5-iodo-1,3-dimethyl-;5-IODO-1,3-DIMETHYLURACIL USP/EP/BP
CAS:40738-83-8
MF:C6H7IN2O2
MW:266.04
EINECS:
Product Categories:pyrimidine;Heterocycle-Pyrimidine series;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Pyrimidines;PyrimidinesHeterocyclic Building Blocks
Mol File:40738-83-8.mol
5-IODO-1,3-DIMETHYLURACIL Structure
5-IODO-1,3-DIMETHYLURACIL Chemical Properties
Melting point 225 °C (dec.)(lit.)
Boiling point 261.3±43.0 °C(Predicted)
density 2.04±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,2-8°C
solubility DMSO: soluble10mg/mL(lit.)
pka-3.54±0.40(Predicted)
Sensitive Light Sensitive
CAS DataBase Reference40738-83-8
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-42/43-63
Safety Statements 22-26-36/37/39-45
WGK Germany 3
HS Code 29335990
MSDS Information
ProviderLanguage
SigmaAldrich English
ALFA English
5-IODO-1,3-DIMETHYLURACIL Usage And Synthesis
Uses5-Iodo-1,3-dimethyluracil may be used for the synthesis of N-[2-[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)thio]-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)yl]methanesulfonamide.
General DescriptionThe effect of 5-iodo-1,3-dimethyluracil on the incorporation of [125I] 5-iodo-2′-deoxyuridine [125I radiolabelled IdUrd] in DNA of cancer cells has been studied. Synthesis of 5-iodo-1,3-dimethyluracil from aromatic organomercurials; 5-(acetoxymercurio)-1,3-dimethyluracil or 5,5′-mercuriobis(1,3-dimethyluracil) has been reported.
5-IODO-1,3-DIMETHYLURACIL Preparation Products And Raw materials
Uracil 5-IODO-1,3-DIMETHYLURACIL 1,2,3,4-TETRAHYDRO-5-IODO-1,3,6-TRIMETHYL-2,4-DIOXOPYRIMIDINE 1,3-Dimethyluracil 5-Iodouracil (AS)-ALPHA-AMINO-3-[(4-CARBOXYPHENYL)METHYL]-3,4-DIHYDRO-5-IODO-2,4-DIOXO-1(2H)-PYRIMIDINEPROPANOIC ACID

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