Edoxaban Impurity 12 (1R,2R,4S)

Edoxaban Impurity 12 (1R,2R,4S) Basic information
Product Name:Edoxaban Impurity 12 (1R,2R,4S)
Synonyms:EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]-;N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(diMethylcarbaMoyl)-2-(5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxaMido)cyclohexyl)oxalaMide;N1-(5-chloro-2-pyridinyl)-N2-[(1R,2R,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide;Edoxaban Isomer (RRS);N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide;Enantiomer(RRS);Edoxaban impurity 7/Edoxaban RRS Isomer;Edoxaban impurity 7/1-epi-Edoxaban/Edoxaban RRS Isomer/N1-(5-chloropyridin-2-yl)-N2-((1R,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
CAS:500572-10-1
MF:C24H30ClN7O4S
MW:548.06
EINECS:
Product Categories:
Mol File:500572-10-1.mol
Edoxaban Impurity 12 (1R,2R,4S) Structure
Edoxaban Impurity 12 (1R,2R,4S) Chemical Properties
density 1.43±0.1 g/cm3(Predicted)
pka9.46±0.70(Predicted)
Safety Information
MSDS Information
Edoxaban Impurity 12 (1R,2R,4S) Usage And Synthesis
Uses1-epi-Edoxaban is an impurity of Edoxaban (E555520) which is an anticoagulant drug which acts as a direct factor Xa inhibitor.
Edoxaban Impurity 12 (1R,2R,4S) Preparation Products And Raw materials
2-BroMo-5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride (1R,3S,4R)-3-Amino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester hydrochloride Edoxaban Impurity 37 Edoxaban Impurity 42 (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid EthanediaMide, N1-(5-chlo... carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester 2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid EthanediaMide iMpurity D Edoxaban Impurity 23 Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1R,2S,4S)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- EthanediaMide, N1-(5-chlo... Edoxaban M6

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