ChemicalBook Product Catalog Analytical Chemistry Standard Pharmaceutical Impurity Reference Standards (R)-(+)-Tolvaptan

(R)-(+)-Tolvaptan

(R)-(+)-Tolvaptan Basic information
Product Name:(R)-(+)-Tolvaptan
Synonyms:(R)-(+)-Tolvaptan;Tolvaptan (R)-Isomer;Tolvaptan Impurity R-Isomer;Benzamide, N-[4-[[(5R)-7-chloro-2,3,4,5-tetrahydro-5-hydroxy-1H-1-benzazepin-1-yl]carbonyl]-3-methylphenyl]-2-methyl-
CAS:331947-66-1
MF:C26H25ClN2O3
MW:448.94
EINECS:
Product Categories:Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:331947-66-1.mol
(R)-(+)-Tolvaptan Structure
(R)-(+)-Tolvaptan Chemical Properties
Melting point >167°C (dec.)
storage temp. Refrigerator
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White
Safety Information
MSDS Information
(R)-(+)-Tolvaptan Usage And Synthesis
UsesAn enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist used to treat hyponatremia (low blood sodium levels) associated with congestive heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
UsesAn enantiomer of Tolvaptan. It is a selective, competitive arginine vasopressin V2 receptor antagonist irrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH).
(R)-(+)-Tolvaptan Preparation Products And Raw materials
(S)-(-)-Tolvaptan N-[4-[(7-Chloro-2,3,4,5-tetrahydro-5-oxo-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide
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