JWH 412

JWH 412 Basic information
Product Name:JWH 412
Synonyms:JWH 412;(4-fluoronaphthalen-1-yl)-(1-pentylindol-3-yl)methanone;Methanone, (4-fluoro-1-naphthalenyl)(1-pentyl-1H-indol-3-yl)-
CAS:1364933-59-4
MF:C24H22FNO
MW:359.44
EINECS:
Product Categories:Aromatics, Heterocycles, Indole Derivatives, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File:1364933-59-4.mol
JWH 412 Structure
JWH 412 Chemical Properties
Boiling point 539.3±30.0 °C(Predicted)
density 1.14±0.1 g/cm3(Predicted)
solubility DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
form A crystalline solid
Safety Information
MSDS Information
JWH 412 Usage And Synthesis
DescriptionJWH 412 is a positional isomer of AM2201 that was identified in the ‘herbal mixture’ XoXo. The substitution of hydrogen against fluorine in the 4-position of the naphthyl moiety enhances the binding affinity to the central cannabinoid (CB1) receptor compared to the unsubstituted JWH 018. JWH 412 demonstrates Ki values of 7.2 and 3.2 nM at CB1 and peripheral CB2 receptors, respectively. This product is intended for research and forensic purposes.
UsesJWH 412 is a positional isomer of AM2201 that was identified in the ‘herbal mixture’ XoXo. The substitution of hydrogen against fluorine in the 4-position of the naphthyl moiety enhances the binding affinity to the central cannabinoid (CB1) receptor compared to the unsubstituted JWH 018. JWH 412 demonstrates Ki values of 7.2 and 3.2 nM at CB1 and peripheral CB2 receptors, respectively. This product is intended for research and forensic purposes.[Cayman Chemical]
UsesJWH 412 is a naphthoylindoles acting on cannabinoid receptors identified based on their fragmentation patterns under ESI-QTOFMS.
JWH 412 Preparation Products And Raw materials

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