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| | 2-Pyridinethiol 1-oxide Basic information |
| Product Name: | 2-Pyridinethiol 1-oxide | | Synonyms: | MercaptypyridineNoxideanhydrous;N-Hydroxy-2-thiopyridone;pyridine-2-thiol N-oxide;2-MERCAPTOPYRIDINE-N-OXIDE 99%;2-MERCAPTOPYRIDINE N-OXIDE SODIUM SALT ANHYDROUS, 98%;PYRIDINETHIOLOXIDE;Pyrithione (and/or unspecified salts);2-MERCAPTOPYRIDINE-N-OXIDE 90% ,PYRITHIONE 90% | | CAS: | 1121-31-9 | | MF: | C5H5NOS | | MW: | 127.16 | | EINECS: | 214-329-4 | | Product Categories: | PYRIDINE | | Mol File: | 1121-31-9.mol |  |
| | 2-Pyridinethiol 1-oxide Chemical Properties |
| Melting point | 69-72 °C (lit.) | | Boiling point | 350.2±15.0 °C(Predicted) | | density | 1.255 (estimate) | | refractive index | 1.5480 (estimate) | | storage temp. | Refrigerator | | solubility | Soluble in tris-hydrochloric acid. | | form | Powder, Crystals, and/or Chunks | | pka | 5.40±0.50(Predicted) | | color | Off-white to beige or yellow to yellow-greenish or grayish-green | | Sensitive | Air & Light Sensitive | | Merck | 14,7994 | | BRN | 906983 | | Stability: | Stable. Incompatible with strong bases, strong oxidizing agents. | | CAS DataBase Reference | 1121-31-9(CAS DataBase Reference) | | NIST Chemistry Reference | 2-Mercaptopyridine-n-oxide(1121-31-9) | | EPA Substance Registry System | 2-Pyridinethiol, 1-oxide (1121-31-9) |
| | 2-Pyridinethiol 1-oxide Usage And Synthesis |
| Chemical Properties | off-white powder | | Uses | 2-Mercaptopyridine N-oxide is used in ratiometric fluorescence imaging of intracellular zinc ions in mammalian cultures. It is used in the radical coupling of benzoyl derivatives of 2-deoxy-D-ribose, with heterocyclic bases to give C-nucleosides. It acts as a ligand and form coordination complexes with palladium chloride. It is a precursor to O-acyl thiohydroxamates. Further, it serves as an antifungal agent. In addition to this, it is used in the preparation of 1-oxa-2-oxo-3-thia-indolizinium chloride by reaction with carbonyl dichloride. | | Uses | Precursor to O-acyl thiohydroxamates. Ligates to metals to form biologically active complexes. | | Definition | ChEBI: Pyrithione is a pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent. It has a role as an ionophore. It is a pyridinethione and a monohydroxypyridine. It is a tautomer of a pyridine-2-thiol N-oxide. | | General Description | 2-Mercaptopyridine N-oxide forms complexes on reaction with palladium chloride. It inhibits NADH-fumarate reductase purified from Trypanosoma cruzi. It is precursor to O-acyl thiohydroxamates. It ligates to metals to form biologically active complexes. |
| | 2-Pyridinethiol 1-oxide Preparation Products And Raw materials |
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