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| | hygromycin A Basic information |
| Product Name: | hygromycin A | | Synonyms: | hygromycin A;5-Deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-5-hexosulofuranosyl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propenyl]amino]-1-O,2-O-methylene-D-neo-inositol;Antibiotic WS-1627B;Homomycin;Hygromycin;D-neo-Inositol, 5-deoxy-5-[[(2E)-3-[4-[(6-deoxy-β-D-arabino-hexofuranos-5-ulos-1-yl)oxy]-3-hydroxyphenyl]-2-methyl-1-oxo-2-propen-1-yl]amino]-1,2-O-methylene-;Homomycin A;(E)-N-[(3aS,4R,5R,6S,7R,7aR)-4,6,7-trihydroxy-3a,4,5,6,7,7a-hexahydro-1,3-benzodioxol-5-yl]-3-[4-[(2S,3S,4S,5S)-5-acetyl-3,4-dihydroxyoxolan-2-yl]oxy-3-hydroxyphenyl]-2-methylprop-2-enamide | | CAS: | 6379-56-2 | | MF: | C23H29NO12 | | MW: | 511.48 | | EINECS: | | | Product Categories: | | | Mol File: | 6379-56-2.mol |  |
| | hygromycin A Chemical Properties |
| Melting point | 105-109°; mp 110-112° (dec) (Chida) | | alpha | D25 -126° (c = 1 in water) | | Boiling point | 925.5±65.0 °C(Predicted) | | density | 1.60±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: 12 mg/mL,PBS (pH 7.2): 10 mg/mL | | form | A solid | | pka | 8.9(at 25℃) | | InChIKey | YQYJSBFKSSDGFO-MZHPCZETNA-N | | SMILES | [C@H]12OCO[C@H]1[C@@H](O)[C@H](O)[C@H](NC(=O)/C(/C)=C/C1=CC=C(O[C@H]3[C@@H](O)[C@H](O)[C@@H](C(=O)C)O3)C(O)=C1)[C@@H]2O |&1:0,4,5,7,9,21,22,24,26,34,r| | | CAS DataBase Reference | 6379-56-2 |
| | hygromycin A Usage And Synthesis |
| Chemical Properties | White powder. Weakly acidic. Freely
soluble in water and alcohol. Produced by Streptomyces hygroscopicus. | | Uses | Hygromycin A, a neglected antibiotic, selectively kills the bacteria that cause Lyme disease. It was able to treat Lyme disease in mice without disrupting the microbiome. | | Uses | Medicine (broad-spectrum antibiotic). | | Definition | ChEBI: A natural product found in Streptomyces species. |
| | hygromycin A Preparation Products And Raw materials |
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