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Cidofovir

Cidofovir Basic information
Product Name:Cidofovir
Synonyms:Cidofovir hydrate;Drg-0145;Gs-0504;Phosphonic acid, ((2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)-, dihydrate, (S)-;Unii-jil713Q00n;(S)-[1-(4-AMino-2-oxo-pyriMidin-1(2H)-yl)-3-hydroxy-propan-2-yl]oxyMethylphosphonic acid dihydrate;Cidofovir hydrate (1:2);P-[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid hydrate (1:2)
CAS:149394-66-1
MF:C8H14N3O6P
MW:279.187021
EINECS:814-987-8
Product Categories:Anti-virals;Heterocyles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Amines;API
Mol File:149394-66-1.mol
Cidofovir Structure
Cidofovir Chemical Properties
Melting point >250°C (dec.)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Sparingly), Water (Sparingly)
form Solid
color White
InChIInChI=1/C8H14N3O6P/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16)/t6-/s3
InChIKeyVWFCHDSQECPREK-ISZMHOAENA-N
SMILESN1C(=O)N(C[C@@H](CO)OCP(O)(=O)O)C=CC=1N |&1:5,r|
Safety Information
HS Code 2933599550
MSDS Information
Cidofovir Usage And Synthesis
Chemical PropertiesWhite Solid
UsesAn injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefo re prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV).
UsesCidofovir Dihydrate is used in treatment of pain and combination with analgesics.
DefinitionChEBI: The dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.
Brand nameVistide (Gilead Sciences).
Cidofovir Preparation Products And Raw materials
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