4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Chemical Properties
Melting point
>240°C (dec.)
storage temp.
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility
DMSO (Slightly)
form
Solid
color
White to Off-White
Water Solubility
100vol% at 20℃[vol%]
Stability:
Hygroscopic, Moisture Sensitive
Safety Information
MSDS Information
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Usage And Synthesis
Uses
4-((4-Methylpiperazin-1-yl)methyl)benzoyl Chloride Dihydrochloride is an intermediate in the synthesis of Gleevec N-4-((4-Methylpiperazin-1-yl)methyl)benzaldehyde (G407010), an impurity of Gleevec (G407000), a tyrosine kinase inhibitor which is highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
4-(4-Methylpiperazinylmethyl)benzoyl chloride dihydrochloride Preparation Products And Raw materials
