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| | L-tert-Leucine Chemical Properties |
| Melting point | ≥300 °C (lit.) | | alpha | 6.3 º (c=4, 6 N HCl 200 ºC) | | Boiling point | 217.7±23.0 °C(Predicted) | | density | 1.1720 (estimate) | | refractive index | -9 ° (C=3, H2O) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | 1 M HCl: 50 mg/mL | | pka | 2.39±0.12(Predicted) | | form | powder | | color | White to almost white | | optical activity | [α]20/D 9.5°, c = 3 in H2O | | Water Solubility | 125.5 g/L (20 ºC) | | BRN | 1721824 | | InChIKey | NPDBDJFLKKQMCM-SCSAIBSYSA-N | | CAS DataBase Reference | 20859-02-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Safety Statements | 22-24/25 | | WGK Germany | 3 | | RTECS | OH2850000 | | Hazard Note | Irritant | | HS Code | 29224999 |
| | L-tert-Leucine Usage And Synthesis |
| Description | L-tert-Leucine is an essential amino acid making up one third of our muscle protein. L-tert-leucine is important in developing chiral pharmaceutically active chemicals. It can be used as a food additive. It is used in the formation of sterols. It can also be used as the catalyst in the production of cobalt oxazoline palladacycles complex. It can also be used for the production of Chiral tridentate Schiff base ligands.
| | References | Korkmaz, Neslihan, D. Astley, and S. T. Astley. "Tridentate ligands derived from L-tert-Leucine for the Cu(II) mediated asymmetric Henry reaction." Turkish Journal of Chemistry 35.3(2011):1-17.
https://www.alfa.com/en/catalog/L13707/
http://igem.org/abstract_pdf_file.cgi?id=1719
| | Chemical Properties | White to almost white powder | | Uses | L-tert-Leucine is an essential amino acid and makes up one third of our muscle protein. It can be used as a food additive. It is used in the formation of sterols. It is used in the production of cobalt oxazoline palladacycles complex, which acts as a catalyst in the rearrangement of prochiral N-aryl trifluoroacetimidates to allylic amides yielded in significantly higher enantioselectivities with the (S)-(pR)-diasteroisomer. | | Synthesis Reference(s) | Organic Syntheses, Coll. Vol. 3, p. 523, 1955
Tetrahedron Letters, 19, p. 4625, 1978 DOI: 10.1016/S0040-4039(01)85688-4 |
| | L-tert-Leucine Preparation Products And Raw materials |
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