ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Other amino acid derivatives 5-AMINOVALERIC ACID

5-AMINOVALERIC ACID

5-AMINOVALERIC ACID Basic information
Product Name:5-AMINOVALERIC ACID
Synonyms:5-Aminovaleric acid≥ 98% (HPLC);H2N(CH2)4COOH;5-AMinovaleric acid, 97% 5GR;Pentanoic acid, 5-amino-;Valeric acid, 5-amino-;DELTA-AMINOVALERIC ACID;DELTA-AMINO-N-VALERIC ACID;H-APE(5)-OH
CAS:660-88-8
MF:C5H11NO2
MW:117.15
EINECS:211-544-5
Product Categories:omega-Aminocarboxylic Acids;omega-Functional Alkanols, Carboxylic Acids, Amines & Halides;Amino Acids and Derivatives;Miscellaneous
Mol File:660-88-8.mol
5-AMINOVALERIC ACID Structure
5-AMINOVALERIC ACID Chemical Properties
Melting point 158-161 °C(lit.)
Boiling point 247.5±23.0 °C(Predicted)
density 1.2000 (estimate)
refractive index 1.4650 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
form Crystalline Powder
pka4.27(at 25℃)
color White to off-white
BRN 906833
CAS DataBase Reference660-88-8(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
HS Code 29224999
MSDS Information
ProviderLanguage
ACROS English
SigmaAldrich English
ALFA English
5-AMINOVALERIC ACID Usage And Synthesis
Chemical Propertieswhite to off-white crystalline powder
Uses5-Aminovaleric acid (5-AVA) is used:
  • In the preparation of (5-AVA)x(MA)1-xPbI3, a perovskite for fabricating printable mesoscopic perovskite solar cell.
  • As a spacer in the synthesis of rhenium and technetium-99m labeled insulin.
  • To synthesize dipeptides that self-assemble to form nanotubes in the solid state as well as in solution over a wide range of pH.
  • As a starting material in the total synthesis of an alkaloid, lycoposerramine Z.

Uses5-Aminovaleric Acid is used in the development of drugs that halts severe type of seizures.
DefinitionChEBI: A delta-amino acid comprising pentanoic acid with an amino substituent at C-5; a methylene homologue of gamma-aminobutyric acid (GABA) that is a weak GABA agonist.
Purification MethodsCrystallise it from H2O/EtOH. When heated above its melting point, it is converted to 2-piperidone with m 200o. [Wood & Colver J Am Chem Soc 67 654 1945, Beilstein 4 IV 2636.]
5-AMINOVALERIC ACID Preparation Products And Raw materials
Preparation ProductsN-Succinimidyl 6-maleimidohexanoate-->delta-guanidinovaleric acid-->FMOC-5-AMINOPENTANOIC ACID-->N-Boc-cadaverine-->Boc-5-aminopentanoic acid-->MFCD01995662-->2-Piperidinone, 1-(3,5-dimethylphenyl)--->5-(1H-pyrrol-1-yl)pentanoic acid-->ETHYL 5-AMINOVALERATE
BOC-D-2-AMINOVALERIC ACID N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-norvaline, (S)-N-alpha-Fmoc-2-aminovaleric acid (R)-2-Aminopentanoic acid (R)-1,2-dimethylpropyl ester 5-[(4-Amino-1,2-dihydro-2-oxopyrimidin)-1-yl]-4-aminopentanoic acid 4-[(4-Amino-1,2-dihydro-2-oxopyrimidin)-1-yl]-5-aminopentanoic acid (2R)-3-Hydroxy-2-aminopentanoic acid (2S)-2-Aminopentanoic acid, N-BOC protected 98%,N-ALPHA-T-BUTYLOXYCARBONYL-L-NORVALINE, (S)-N-ALPHA-BOC-2-AMINOVALERIC ACID,BOC-L-2-AMINOVALERIC ACID [R,(-)]-2-Aminovaleric acid ethyl ester (R)-2-Aminopentanoic acid (R)-1-methylpropyl ester (S)-2-Aminopentanoic acid (R)-1,2-dimethylpropyl ester (S)-2-[[4-[[(2-Amino-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidine-6-yl)methyl]amino]benzoyl]amino]-5-aminopentanoic acid ACETYL-DL-2-AMINOVALERIC ACID L-Norvaline 2-(2H-BENZO[3,4-D]1,3-DIOXOLEN-5-YL)(2S)-2-AMINOPENTANOIC ACID Boc-N-Me-L-2-aminovaleric acid (4R)-4-Aminopentanoic acid,[R,(+)]-4-Aminovaleric acid Z-L-alpha-aminovaleric acid-N-hydroxysuccinimide e (R)-2-Aminopentanoic acid methyl ester,(R)-2-Aminovaleric acid methyl ester
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