N-Cbz-L-serine methyl ester

N-Cbz-L-serine methyl ester Basic information
Product Name:N-Cbz-L-serine methyl ester
Synonyms:N-CARBOBENZOXY-L-SERINE METHYL ESTER;N-CARBOBENZYLOXY-L-SERINE METHYL ESTER;N-CBZ-L-SERINE METHYL ESTER;CBZ-L-Serine methyleester;methyl ((benzyloxy)carbonyl)-L-serinate;L-Serine, N-[(phenylmethoxy)carbonyl]-, methyl ester;(S)-3-Hydroxy-2-(benzyloxycarbonylamino)propionic acid methyl ester;[(S)-3-Hydroxy-1-oxo-1-methoxypropan-2-yl]carbamic acid benzyl ester
CAS:1676-81-9
MF:C12H15NO5
MW:253.25
EINECS:605-484-2
Product Categories:Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids;Amino Acid Derivatives;Peptide Synthesis;Serine
Mol File:1676-81-9.mol
N-Cbz-L-serine methyl ester Structure
N-Cbz-L-serine methyl ester Chemical Properties
Melting point 41-43 °C(lit.)
Boiling point 170 °C0.01 mm Hg(lit.)
density 1.2499 (rough estimate)
refractive index -15 ° (C=1, MeOH)
Fp >230 °F
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform, Methanol
pka10.49±0.46(Predicted)
form Viscous Liquid or Solid
color Pale yellow
CAS DataBase Reference1676-81-9(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29242990
MSDS Information
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SigmaAldrich English
N-Cbz-L-serine methyl ester Usage And Synthesis
Chemical PropertiesClear Waxy Solid
UsesN-Cbz-L-serine methyl ester is used to inhibit the activity of Mycobacterium tuberculosis in studies. Also used in the synthesis of pyrazinecarboxamide-based compounds acting as inhibitors of diacylglycerol acetyltransferases regarding treatment of obesity.
UsesN-[(Phenylmethoxy)carbonyl]-L-serine Methyl Ester is used to inhibit the activity of Mycobacterium tuberculosis in studies. Also used in the synthesis of pyrazinecarboxamide-based compounds acting as inhibitors of diacylglycerol acetyltransferases regarding treatment of obesity.
N-Cbz-L-serine methyl ester Preparation Products And Raw materials
Preparation ProductsL-SERINE METHYL ESTER-->(S)-BENZYL 4-FORMYL-2,2-DIMETHYLOXAZOLIDINE-3-CARBOXYLATE-->(S)-3-BENZYL 4-METHYL 2,2-DIMETHYLOXAZOLIDINE-3,4-DICARBOXYLATE
N-Cbz-O-tert-butyl-L-serine N-CARBOBENZOXY-L-SERINE BETA-LACTONE Nequinate Methyl L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE Cbz-L-Threonine benzyl ester N-CARBOBENZOXY-L-THREONINE-P-NITROPHENYL ESTER Z-THR(TBU)-OME Z-THR-ONB Z-SER(TBU)-ONB Z-THR(TBU)-ONB Z-THR(TBU)-OTBU Z-THR-OTBU Kresoxim-methyl Thiophanate-methyl Z-SER(TBU)-OTBU N-Carbobenzyloxy-L-threonine methyl ester METSULFURON METHYL

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