2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Basic information
Product Name:2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate
Synonyms:MECLOFENOXATE;Meclofenoxatum;DIMETHYLAMINOETHYLPARA-CHLOROPHENOXYACETATE;2-(DIMETHYLAMINO)ETHYLPARA-CHLOROPHENOXYACETATE;(4-chlorophenoxy)-acetic acid 2-(dimethylamino)ethyl ester;Meclofenoxate (base and/or unspecified salts);2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate;2-(4-chlorophenoxy)acetic acid 2-dimethylaminoethyl ester
CAS:51-68-3
MF:C12H16ClNO3
MW:257.71
EINECS:200-116-3
Product Categories:
Mol File:51-68-3.mol
2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Structure
2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Chemical Properties
Melting point 138-140 °C
Boiling point 180 °C(Press: 9-10 Torr)
density 1.2038 (rough estimate)
refractive index 1.5200 (estimate)
pka8.17±0.28(Predicted)
NIST Chemistry ReferenceMeclofenoxate(51-68-3)
Safety Information
MSDS Information
2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Usage And Synthesis
Chemical PropertiesThe commodity of meclofenoxate is hydrochloride (C12H16CINO3·HCL, [3685-84-5]), also known as Lucidril, Brenal, etc. It is a white crystalline powder with a melting point of 135-139°C. Easily soluble in water, insoluble in ether, benzene and chloroform. The taste is sour and bitter, and it is easy to decompose and fail when exposed to moisture.
UsesMeclofenoxate is a central nervous system stimulant. It mainly acts on the cerebral cortex, promotes the redox of brain cells, increases the utilization of sugar, can regulate the metabolism of nerve cells, and promote the excitation of the nervous system in a state of inhibition. It is an effective drug for stimulating the spirit and inhibiting fatigue.
DefinitionChEBI: Meclofenoxate is a monocarboxylic acid.
Side effectsOccasionally can cause excitement, insomnia, blood pressure changes, vascular pain or fatigue.
SynthesisMeclofenoxate can be prepared by esterification of p-chlorophenoxyacetic acid, dimethylaminoethanol, m-xylene and p-toluenesulfonic acid.
2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Preparation Products And Raw materials
Raw materialsPhosphorus oxychloride-->p-Toluenesulfonic acid-->m-Xylene-->PARA TOLUENE-->2-Dimethylaminoethanol-->4-Chlorophenoxyacetic acid
cerebrolysin Donepezil Methotrexate Cimetidine Cyclophosphamide monohydrate Vinblastine sulfate Meclofenoxate hydrochloride TOSLAB 860558 Biclofibrate AURORA 7699 Bis(2-(dimethylamino)ethyl) (4-chlorophenoxy)butanedioate ethanedioate (1:2) 4-Chlorophenoxyacetic acid 2-(3-Oxo-2-(2-thienyl)-1-piperazinyl)ethyl (4-chlorophenoxy)acetate 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate

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