Benzydamine

Benzydamine Basic information
Product Name:Benzydamine
Synonyms:1-benzyl-3-(3-(dimethylamino)propoxy)-1h-indazol;1-Benzyl-3-(3-(dimethylamino)propoxy)-1H-indazole;1H-Indazole, 1-benzyl-3-(3-(dimethylamino)propoxy)-;benzidamine;Benzindamine;N-(3-[(1-Benzyl-1H-indazol-3-yl)oxy]propyl)-N,N-dimethylamine;AURORA KA-7514;BENZYDAMINE
CAS:642-72-8
MF:C19H23N3O
MW:309.41
EINECS:211-388-8
Product Categories:API intermediates
Mol File:642-72-8.mol
Benzydamine Structure
Benzydamine Chemical Properties
Melting point 167-170 °C
Boiling point bp0.05 160°
density 1.1106 (rough estimate)
refractive index 1.5900 (estimate)
storage temp. Refrigerator
solubility Chloroform (Sparingly), Methanol (Slightly)
form Oil
pka9.25±0.28(Predicted)
color Orange
Stability:No Data Aavailable
CAS DataBase Reference642-72-8(CAS DataBase Reference)
NIST Chemistry Reference1-Propanamine, n,n-dimethyl-3-[[1-(phenylmethyl)-1h-indazol-3-yl]oxy]-(642-72-8)
Safety Information
ToxicityLD50 orl-rat: 9500 mg/kg ARZNAD 22,711,72
MSDS Information
Benzydamine Usage And Synthesis
DescriptionBenzydamine is an analytical reference standard categorized as an analgesic. Benzydamine has been abused and is associated with hallucinations, muscle weakness, and excitability. This product is intended for research and forensic applications.
UsesBenzydamine is a nonsteroidal anti-inflammatory drug with local anaesthetic, analgesic and antipyretic properties.
UsesAnalgesic; antipyretic; anti-inflammatory.
DefinitionChEBI: Benzydamine is a member of the class of indazoles carrying benzyl and 3-(dimethylamino)propyl groups at positions 1 and 3 respectively. A locally-acting nonsteroidal anti-inflammatory drug that also exhibits local anaesthetic and analgesic properties. It has a role as a central nervous system stimulant, a non-steroidal anti-inflammatory drug, a hallucinogen, a local anaesthetic and an analgesic. It is a member of indazoles, an aromatic ether and a tertiary amino compound. It is a conjugate base of a benzydamine(1+).
Brand nameTantum (Angelini Francesco, Italy).
Safety ProfilePoison by intraperitoneal andintravenous routes. Moderately toxic by ingestion andsubcutaneous routes. When heated to decomposition itemits toxic fumes of NOx.
Benzydamine Preparation Products And Raw materials
Preparation ProductsBenzydamine hydrochloride
Benzydamine hydrochloride BENZYDAMINE N-OXIDE HYDROGEN MALEATE Propyl gallate Benzyl chloride Benzyltriethylammonium chloride 3-Indazolinone Dimethyldimethoxysilane Phenylacetone Benzyl alcohol 3-Dimethylaminopropylamine Benzyltrimethylammonium chloride 1-methylindazole Diethoxydimethylsilane Benzyl Benzyl acetate 1-Benzyl-3-hydroxy-1H-indazole N,N-Dimethyl-1,4-phenylenediamine Benzydamine

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