HARMALINE

HARMALINE Basic information
Product Name:HARMALINE
Synonyms:1-METHYL-7-METHOXY-3,4-DIHYDRO-BETA-CARBOLINE;TIMTEC-BB SBB003407;1-Methyl-7-methoxy-3,4-dihydroxy-beta-carboline;1-methyl-7-methoxy-3,4-dihydro-β-carboline;HARMALINE(EXTRACTFORMPEGANUMHARMALAROOTS);3,4-Dihydro-7-methoxy-1-methyl-beta-carboline 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole Dihydroharmine;NSC 407285;PYRIDE(3,4-B)INDOLE,4,9-DIHYDRO-7-METHOXY-1-METHYL-
CAS:304-21-2
MF:C13H14N2O
MW:214.26
EINECS:206-152-6
Product Categories:Inhibitors;Indoles and derivatives;Heterocyclic Compounds
Mol File:304-21-2.mol
HARMALINE Structure
HARMALINE Chemical Properties
Melting point 232-234 °C(lit.)
alpha ±0°
Boiling point 354.4°C (rough estimate)
density 1.0850 (rough estimate)
refractive index 1.6450 (estimate)
solubility DMF: 1.4 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 0.25 mg/ml; Ethanol: 0.5 mg/ml
Water Solubility Slightly soluble in water
pka4.2(at 25℃)
form powder
color Light orange to Yellow to Green
Merck 14,4613
BRN 207310
LogP2.251 (est)
CAS DataBase Reference304-21-2(CAS DataBase Reference)
NIST Chemistry ReferenceHarmaline(304-21-2)
EPA Substance Registry System3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl- (304-21-2)
Safety Information
Hazard Codes Xn
Risk Statements 25-20/21/22
Safety Statements 22-24/25-36
RIDADR 1544
WGK Germany 3
RTECS UU9800000
HS Code 2939.80.0000
HazardClass 6.1(b)
PackingGroup III
Hazardous Substances Data304-21-2(Hazardous Substances Data)
MSDS Information
ProviderLanguage
SigmaAldrich English
HARMALINE Usage And Synthesis
UsesCNS stimulant, antiparkinsonian agent
UsesCNS stimulant; may act through NMDA receptors. Reversible inhibitor of MAO-A
DefinitionChEBI: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.
Synthesis Reference(s)Canadian Journal of Chemistry, 37, p. 1851, 1959 DOI: 10.1139/v59-272
Purification MethodsRecrystallise harmaline from MeOH and sublime it at high vacuum. It has UV in MeOH a
1-chloro-3,5-dimethoxy-2-nitrobenzene 6-Hydroxyindole 2,3-DIMETHYL-6-METHOXYINDOLE 2-ETHYLPYRROLE 3-Methylindole 6-Methoxyindole Pyrrole 6-hydroxytryptamine 3-(2-Aminoethyl)-6-methoxyindole 3-METHYLPYRROLE HARMALOL N-PROPYLETHYLIDENEAMINE Indole 2-METHYL-1H-PYRROLE 2-Ethyl-1H-indole HARMALINE 2,3-Dimethylindole harmaline hydrochloride

Email:[email protected] [email protected]
Copyright © 2024 Mywellwork.com All rights reserved.