ChemicalBook Product Catalog Organic Chemistry Carboxylic acids and derivatives Carboxylic acid halides Diphenylacetyl chloride

Diphenylacetyl chloride

Diphenylacetyl chloride Basic information
Product Name:Diphenylacetyl chloride
Synonyms:alpha-phenylbenzeneacetyl chloride;DIPHENYLACETYL CHLORIDE, TECH., 90%;DiphenylacetylChloride97.5%;Diphenylacetylchloride, 97.50%;diphenylaceticacidchloride;diphenyl-acetylchlorid;Dpac;TIMTEC-BB SBB006586
CAS:1871-76-7
MF:C14H11ClO
MW:230.69
EINECS:217-493-5
Product Categories:Pharmaceutical Intermediates;Acid Halides;Carbonyl Compounds;Organic Building Blocks
Mol File:1871-76-7.mol
Diphenylacetyl chloride Structure
Diphenylacetyl chloride Chemical Properties
Melting point 49-53 °C (lit.)
Boiling point 175-176 °C/17 mmHg (lit.)
density 1.1223 (rough estimate)
refractive index 1.5260 (estimate)
Fp >230 °F
storage temp. Store below +30°C.
solubility Chloroform (Slightly), DMSO (Slightly)
form Crystalline Powder
color Slightly yellow
Sensitive Moisture Sensitive
Merck 14,3316
BRN 1211588
CAS DataBase Reference1871-76-7(CAS DataBase Reference)
NIST Chemistry ReferenceDiphenylacetyl chloride(1871-76-7)
Safety Information
Hazard Codes C
Risk Statements 34-36/37
Safety Statements 26-27-28-36/37/39-45
RIDADR UN 3261 8/PG 2
WGK Germany 2
RTECS AO6750000
HazardClass 8
PackingGroup II
HS Code 29163900
MSDS Information
ProviderLanguage
Diphenylacetyl chloride English
SigmaAldrich English
ACROS English
ALFA English
Diphenylacetyl chloride Usage And Synthesis
Chemical PropertiesSLIGHTLY YELLOWISH CRYSTALLINE POWDER
UsesDiphenylacetyl Chloride is a reagent used in the synthesis of β-lactam estrogen receptor antagonists promoting antiproliferative and anti-tubulin polymerizatiion activity.
UsesDiphenylacetyl chloride was used as a reagent in regioselective acylation of cyclomalto-oligosaccharides. It was also used in the preparation of N-substituted amides having local anesthetic properties.
Diphenylacetyl chloride Preparation Products And Raw materials
Preparation ProductsDIPHENAMID-->N-(1-hydroxy-2-methylpropan-2-yl)-2,2-diphenylacetamide-->Phenylalanine, N-(diphenylacetyl)- (9CI)-->N-(2-Chlorophenyl)-2,2-diphenylacetamide-->L-Phenylalanine, N-(diphenylacetyl)- (9CI)-->N-diphenylacetylglycine
Methylene Chloride Bromoacetyl chloride 9H-XANTHENE-9-CARBONYL CHLORIDE Calcium chloride Acetyl chloride Zinc chloride Choline chloride Chloroacetyl chloride Chlorodiphenylphosphine Ammonium chloride Phenylacetyl chloride Oxalyl chloride 2-CHLORO-2,2-DIPHENYLACETYL CHLORIDE Potassium chloride Thionyl chloride 1,5-Diphenylcarbazide 2-​[[(2-​ethylphenyl)​(2-​hydroxyethyl)​amino]​methyl]​-​3,​3-​difluoro-Propanenitrile Diphenylacetyl chloride
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