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| | (+/-)4-HDOHE Basic information |
| Product Name: | (+/-)4-HDOHE | | Synonyms: | 4-HYDROXY DOCOSAHEXAENOIC ACID;(+/-)4-HDOHE;(+/-)4-HYDROXY-5E,7Z,10Z,13Z,16Z,19Z-DOCOSAHEXAENOIC ACID;(±)4-HDHA;IFRKCNPQVIJFAQ-PQVBWYSWSA-N;5,7,10,13,16,19-Docosahexaenoic acid, 4-hydroxy-, (5E,7Z,10Z,13Z,16Z,19Z)-;(+/-)4-HDOHE | | CAS: | 90906-40-4 | | MF: | C22H32O3 | | MW: | 344.49 | | EINECS: | | | Product Categories: | | | Mol File: | 90906-40-4.mol |  |
| | (+/-)4-HDOHE Chemical Properties |
| Boiling point | 502.3±50.0 °C(Predicted) | | density | 0.995±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS (pH 7.2): 0.8 mg/ml | | pka | 4.57±0.10(Predicted) |
| | (+/-)4-HDOHE Usage And Synthesis |
| Description | (±)4-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Enzymatic transformation of DHA by RBL-1 cells also produces 4-HDHA. However, the enzymatic product is most likely the S-isomer. (±)4-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid. |
| | (+/-)4-HDOHE Preparation Products And Raw materials |
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