ChemicalBook Product Catalog Biochemical Engineering Amino Acids and Derivatives Alanine derivatives N-(tert-Butoxycarbonyl)-L-alanine

N-(tert-Butoxycarbonyl)-L-alanine

N-(tert-Butoxycarbonyl)-L-alanine Basic information
Product Name:N-(tert-Butoxycarbonyl)-L-alanine
Synonyms:BOC-L-ALANINE;BOC-L-ALANINE-OH;BOC-L-ALA-OH;BOC-L-ALA;BOC-ALA;BOC-ALANINE;BOC-ALA-OH;H-ALPHA-T-BOC-L-ALANINE
CAS:15761-38-3
MF:C8H15NO4
MW:189.21
EINECS:239-847-8
Product Categories:Boc-Amino Acids;Amino Acids (N-Protected);Alanine [Ala, A];Boc-Amino Acids and Derivative;Biochemistry;Boc-Amino acid series;Protected Amino Acids;straight chain compounds;Amino Acids;Amino Acid Derivatives;PROTECTED AMINO ACID & PEPTIDES;Naphthyridines
Mol File:15761-38-3.mol
N-(tert-Butoxycarbonyl)-L-alanine Structure
N-(tert-Butoxycarbonyl)-L-alanine Chemical Properties
Melting point 79-83 °C(lit.)
alpha -26 º (c=2, acetic acid)
Boiling point 324.46°C (rough estimate)
density 1.2321 (rough estimate)
refractive index -25.5 ° (C=2, AcOH)
storage temp. Sealed in dry,2-8°C
solubility DMSO, Methanol
pka4.02±0.10(Predicted)
form Granular Powder
color White
optical activity[α]20/D 25±1°, c = 2% in acetic acid
BRN 1726365
CAS DataBase Reference15761-38-3(CAS DataBase Reference)
EPA Substance Registry SystemL-Alanine, N-[(1,1-dimethylethoxy)carbonyl]- (15761-38-3)
Safety Information
Hazard Codes Xi,Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 24/25-36-26
WGK Germany 3
TSCA Yes
HS Code 2924 19 00
HazardClass IRRITANT
MSDS Information
ProviderLanguage
BOC-L-Alanine English
ACROS English
SigmaAldrich English
ALFA English
N-(tert-Butoxycarbonyl)-L-alanine Usage And Synthesis
Chemical PropertiesWhite to off-white microcrystalline powder
UsesBoc-Ala-OH can be used:
  • In the preparation of N-propargylalanine, a key precursor to generate N-(3-aryl)propylated alanine residues.
  • In the resolution of racemic mixture of 3,3′-bis(benzyloxy)-1,1′-binaphthalene-2,2′-diol.
  • In the one-pot synthesis of hybrid tripeptidomimetics containing both amide and imide functionalities.
Phenprobamate BOC-MET(O)-OH PYRAZOPHOS EC 2.6.1.2 BOC-N-ME-SER-OH L-Alanine CARBONYL SULFIDE tert-Butanol tert-Butyl peroxyacetate L-Alanine Boc-O-(2-bromo-Cbz)-L-Tyrosine BOC-N-Methyl-L-alanine D-Alanine BOC-LYS(TFA)-OH BOC-L-NORLEUCINE BOC-ILE-OSU BOC-TRP-ONP N-(tert-Butoxycarbonyl)-L-alanine
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